Bus Tickets from Panama City, US to Indianapolis

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Previously seen trips

One passenger / one way

  • Departure time: August 17 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: August 19 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: August 17 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: August 19 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: August 17 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: August 18 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: August 17 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: August 18 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: August 17 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: August 18 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Panama City, US to Indianapolis: Trip Overview

Average Ticket PriceUS$130
Average Bus Trip Duration1d 5h
Number of daily buses6
Earliest bus departure7:40am
Distance1066 km
Latest bus departure9:10pm

Panama City to Indianapolis Bus

Busbud helps you find a bus from Panama City to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to Indianapolis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Panama City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Panama City, US - Indianapolis

  1. What is the travel distance from Panama City to Indianapolis?

    It's about 1071 km (664 miles) from Panama City to Indianapolis.

  2. What are the departure and arrival locations for buses traveling from Panama City to Indianapolis?

    Buses departing from Panama City Greyhound Bus Station in Panama City will take you to Greyhound Amtrak Station in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-22
No data
08-23
US$149
Today
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08-25
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08-26
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08-27
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08-28
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08-29
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busbud logoThe cheapest trip from Panama City, US to Indianapolis was searched and found on Aug 23, 2025 with a price of US$149

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Indianapolis, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Indianapolis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Indianapolis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Panama City to Indianapolis.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Indianapolis.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Panama City, US by bus?

Bus from Indianapolis to Panama City, US

Why choose Busbud?

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