Bus Tickets from San Jose, US to Panama City, US

Find affordable bus tickets from San Jose, US to Panama City, US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TueAug 12
from US$158
WedAug 13
ThuAug 14
FriAug 15
SatAug 16
SunAug 17
MonAug 18
TueAug 19

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 12 at
    Departure city: San Jose
    Departure location: Diridon Station
    Arrival time: August 15 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 12 at
    Departure city: San Jose
    Departure location: Diridon Station
    Arrival time: August 14 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: San Jose
    Departure location: Diridon Station
    Arrival time: August 14 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: San Jose
    Departure location: Diridon Station
    Arrival time: August 15 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 8:06 AM PDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus San Jose, US to Panama City, US: Trip Overview

Average Ticket PriceUS$201
Average Bus Trip Duration2d 19h
Number of daily buses2
Earliest bus departure12:55am
Distance3411 km
Latest bus departure11:10pm

San Jose to Panama City Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Jose to Panama City.

Bus service from San Jose to Panama City will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from San Jose, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Jose, US - Panama City, US

  1. How far is San Jose from Panama City?

    The distance between San Jose and Panama City is around 3425 km (2124 miles).

  2. What are the departure and arrival locations for buses traveling from San Jose to Panama City?

    Buses traveling this route start their trip at Diridon Station, in San Jose, and end it at Panama City Greyhound Bus Station, in Panama City.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-08
No data
08-09
US$178
Today
US$291
08-11
US$177
08-12
US$171
08-13
No data
08-14
No data
08-15
No data
busbud logoThe cheapest trip from San Jose, US to Panama City, US was searched and found on Aug 12, 2025 with a price of US$171

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Jose, US to Panama City, US, as early as possible.

You can expect to pay from US$171 to US$291 for a bus ticket from San Jose, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$171 which is on 2025-08-12.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Jose to Panama City but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from San Jose to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Jose to Panama City.

Make a music playlist for your bus ride from San Jose to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to San Jose, US by bus?

Bus from San Jose, US to Panama City, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting San Jose

Buses Leaving from San Jose

Buses Going to San Jose

Popular Buses Connecting Panama City

Buses Leaving from Panama City

Buses Going to Panama City