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- This trip is recommended because it is: Cheapest
- This trip is recommended because it is: FastestDeparture time: August 21 atDeparture city: San JoseDeparture location: Diridon StationArrival time: August 23 atDestination city: Panama CityDestination location: Panama City Beach StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: August 21 atDeparture city: San JoseDeparture location: Diridon StationArrival time: August 23 atDestination city: Panama CityDestination location: Panama City Beach StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Bus San Jose, US to Panama City, US: Trip Overview
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San Jose to Panama City Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Jose to Panama City.
Bus service from San Jose to Panama City will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Panama City from San Jose, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in San Jose and Panama City?
Frequently asked questions for your trip San Jose, US - Panama City, US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Jose, US to Panama City, US was searched and found on Aug 20, 2025 with a price of $127To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Jose, US to Panama City, US, as early as possible.
You can expect to pay from $127 to $367 for a bus ticket from San Jose, US to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $216 which is on 2025-08-23.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Jose to Panama City but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from San Jose to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Jose to Panama City.
Make a music playlist for your bus ride from San Jose to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top traveled bus routes
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Popular Buses Connecting San Jose
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Popular Buses Connecting Panama City
Buses Leaving from Panama City
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Buses Going to Panama City
- Bus from Miami to Panama City
- Bus Tallahassee - Panama City
- Atlanta - Panama City
- Bus from Long Beach to Panama City
- Bus Tampa - Panama City
- Chicago - Panama City
- Bus from Orlando to Panama City
- Bus San Jose - Panama City
- Jacksonville - Panama City
- Bus from Fort Lauderdale to Panama City
- Bus Houston - Panama City
- Dothan - Panama City
- Bus from New Orleans to Panama City
- Bus New York City - Panama City
- Birmingham - Panama City