Bus Tickets from West Palm Beach to Panama City, US

Find affordable bus tickets from West Palm Beach to Panama City, US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayAug 21
TomorrowAug 22
SatAug 23
from US$81
SunAug 24
from US$76
MonAug 25
from US$92
TueAug 26
WedAug 27
ThuAug 28

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 23 at
    Departure city: West Palm Beach
    Departure location: Tri-Rail & Greyhound
    Arrival time: August 24 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 23 at
    Departure city: West Palm Beach
    Departure location: Tri-Rail & Greyhound
    Arrival time: August 23 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 23 at
    Departure city: West Palm Beach
    Departure location: Tri-Rail & Greyhound
    Arrival time: August 23 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 23 at
    Departure city: West Palm Beach
    Departure location: Tri-Rail & Greyhound
    Arrival time: August 23 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus West Palm Beach to Panama City, US: Trip Overview

Average Ticket PriceUS$100
Average Bus Trip Duration14h 15m
Number of daily buses3
Earliest bus departure12:40am
Distance679 km
Latest bus departure9:45pm

West Palm Beach to Panama City Bus

With Busbud, comparing and booking tickets for a bus from West Palm Beach to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from West Palm Beach to Panama City.

From cheap bus tickets to more luxurious buses travelling from West Palm Beach to Panama City, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip West Palm Beach - Panama City, US

  1. What is the travel distance from West Palm Beach to Panama City?

    West Palm Beach and Panama City are 671 km (416 miles) apart.

  2. What are the departure and arrival locations for buses traveling from West Palm Beach to Panama City?

    Buses departing from Tri-Rail & Greyhound in West Palm Beach will take you to Panama City Greyhound Bus Station in Panama City.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-19
US$70
08-20
No data
Today
US$75
08-22
No data
08-23
US$74
08-24
US$69
08-25
US$84
08-26
No data
busbud logoThe cheapest trip from West Palm Beach to Panama City, US was searched and found on Aug 24, 2025 with a price of US$69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from West Palm Beach to Panama City, US, as early as possible.

You can expect to pay from US$69 to US$105 for a bus ticket from West Palm Beach to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$69 which is on 2025-08-24.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from West Palm Beach to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from West Palm Beach to Panama City.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from West Palm Beach to Panama City that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from West Palm Beach to Panama City while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to West Palm Beach by bus?

Bus from Panama City, US to West Palm Beach

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting West Palm Beach

Buses Leaving from West Palm Beach

Buses Going to West Palm Beach

Popular Buses Connecting Panama City

Buses Leaving from Panama City

Buses Going to Panama City