Bus Tickets from Indianapolis to Panama City, US

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TodayAug 24
from US$138
TomorrowAug 25
TueAug 26
WedAug 27
ThuAug 28
FriAug 29
SatAug 30
SunAug 31

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 24 at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: August 25 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 24 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: August 25 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Indianapolis to Panama City, US: Trip Overview

Average Ticket PriceUS$122
Average Bus Trip Duration22h 50m
Number of daily buses5
Earliest bus departure3:35am
Distance1065 km
Latest bus departure11:30pm

Indianapolis to Panama City Bus

Busbud helps you find a bus from Indianapolis to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Indianapolis to Panama City from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - Panama City, US

  1. What is the distance between Indianapolis and Panama City?

    The distance covered from Indianapolis to Panama City is 1071 km (664 miles).

  2. What are the departure and arrival locations for buses traveling from Indianapolis to Panama City?

    Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Panama City Greyhound Bus Station, in Panama City.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-22
No data
08-23
US$100
Today
US$132
08-25
No data
08-26
No data
08-27
No data
08-28
No data
08-29
No data
busbud logoThe cheapest trip from Indianapolis to Panama City, US was searched and found on Aug 23, 2025 with a price of US$100

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Panama City, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Indianapolis and Panama City!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to Panama City, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Panama City.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Panama City.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Indianapolis by bus?

Bus from Panama City, US to Indianapolis

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