Bus Tickets from La Serena, CL to San Antonio, CL

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WedAug 20
from $16
ThuAug 21
FriAug 22
SatAug 23
SunAug 24
MonAug 25
TueAug 26
WedAug 27

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 20 at
    Departure city: La Serena
    Departure location: La Serena (Bus terminal La Serena)
    Arrival time: August 20 at
    Destination city: San Antonio
    Destination location: Terminal Barrancas de San Antonio
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 20 at
    Departure city: La Serena
    Departure location: La Serena (Bus terminal La Serena)
    Arrival time: August 20 at
    Destination city: San Antonio
    Destination location: Terminal Barrancas de San Antonio
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • Departure time: August 20 at
    Departure city: La Serena
    Departure location: La Serena (Bus terminal La Serena)
    Arrival time: August 20 at
    Destination city: San Antonio
    Destination location: Terminal Barrancas de San Antonio
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • Departure time: August 20 at
    Departure city: La Serena
    Departure location: La Serena (Bus terminal La Serena)
    Arrival time: August 20 at
    Destination city: San Antonio
    Destination location: Terminal Barrancas de San Antonio
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • Departure time: August 20 at
    Departure city: La Serena
    Departure location: La Serena (Bus terminal La Serena)
    Arrival time: August 20 at
    Destination city: San Antonio
    Destination location: Terminal Barrancas de San Antonio
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:

Accepted payments

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Bus La Serena, CL to San Antonio, CL: Trip Overview

Average ticket price$18
Average bus trip duration9h 25m
Number of daily buses6
Earliest bus departure6:00am
Distance255 miles (411 km)
Latest bus departure11:59pm

La Serena to San Antonio Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from La Serena to San Antonio.

We make sure you can find a bus service from La Serena to San Antonio from the most reliable bus companies operating this trip.

Discover how much the bus trip from La Serena to San Antonio will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip La Serena, CL - San Antonio, CL

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/16
No data
08/17
No data
Today
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08/19
No data
08/20
$15
08/21
No data
08/22
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08/23
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busbud logoThe cheapest trip from La Serena, CL to San Antonio, CL was searched and found on Aug 20, 2025 with a price of $15

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to San Antonio, CL, as early as possible.

You can expect to pay from $15 to $16 for a bus ticket from La Serena, CL to San Antonio, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $15 which is on 2025-08-20.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from La Serena to San Antonio but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from La Serena to San Antonio, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from La Serena to San Antonio will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from La Serena to San Antonio.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to La Serena, CL by bus?

Bus from San Antonio, CL to La Serena, CL

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