Bus Tickets from Antofagasta to La Serena, CL

Next departures

Next departures for Antofagasta to La Serena on August 31
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Cikbus Elité
Terminal Antofagasta
Terminal de Buses La SerenaCheapest
Pluss Chile
Terminal Antofagasta
Terminal de Buses La SerenaFastest
Cikbus Elité
Terminal Antofagasta
Terminal de Buses La SerenaNo tags
Pluss Chile
Terminal Antofagasta
Terminal de Buses La SerenaNo tags
Andimar
5791 Avenida Iquique
Terminal de Buses La SerenaNo tags

Accepted payments

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Bus Antofagasta to La Serena, CL: Trip Overview

Average ticket price$41
Average bus trip duration11h 30m
Number of daily buses28
Earliest bus departure12:15am
Distance438 miles (705 km)
Latest bus departure11:50pm

Antofagasta to La Serena Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Antofagasta to La Serena.

We make sure you can find a bus service from Antofagasta to La Serena from the most reliable bus companies operating this trip.

Discover how much the bus trip from Antofagasta to La Serena will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Antofagasta - La Serena, CL

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/28
$27
08/29
$32
Today
$32
08/31
$19
09/01
$19
09/02
$19
09/03
$19
09/04
$32
busbud logoThe cheapest trip from Antofagasta to La Serena, CL was searched and found on Sep 2, 2025 with a price of $19

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to La Serena, CL, as early as possible.

You can expect to pay from $19 to $52 for a bus ticket from Antofagasta to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $19 which is on 2025-09-02.

Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Antofagasta to La Serena but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Antofagasta to La Serena, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Antofagasta to La Serena will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Antofagasta to La Serena, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Antofagasta by bus?

Bus from La Serena, CL to Antofagasta

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