Bus Tickets from La Serena, CL to Calama

Find affordable bus tickets from La Serena, CL to Calama with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayAug 11
from $35
TomorrowAug 12
from $33
WedAug 13
from $29
ThuAug 14
from $33
FriAug 15
from $29
SatAug 16
from $33
SunAug 17
from $36
MonAug 18

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 12 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: August 12 at
    Destination city: Calama
    Destination location: Av. Balmaceda
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 12 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: August 13 at
    Destination city: Calama
    Destination location: Terminal de buses Calama
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: August 12 at
    Destination city: Calama
    Destination location: Calama
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: August 13 at
    Destination city: Calama
    Destination location: Av. Balmaceda
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: August 12 at
    Departure city: La Serena
    Departure location: Terminal de Buses La Serena
    Arrival time: August 13 at
    Destination city: Calama
    Destination location: Calama
    Operated by: AndimarAndimar
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus La Serena, CL to Calama: Trip Overview

Average ticket price$40
Average bus trip duration14h 50m
Number of daily buses24
Earliest bus departure12:05am
Distance534 miles (860 km)
Latest bus departure11:59pm

La Serena to Calama Bus

Busbud helps you find a bus from La Serena to Calama. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from La Serena to Calama.

From cheap bus tickets to more luxurious buses traveling from La Serena to Calama, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip La Serena, CL - Calama

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/09
$32
08/10
$33
Today
$33
08/12
$31
08/13
$27
08/14
$31
08/15
$27
08/16
$31
busbud logoThe cheapest trip from La Serena, CL to Calama was searched and found on Aug 13, 2025 with a price of $27

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Calama, as early as possible.

You can expect to pay from $27 to $60 for a bus ticket from La Serena, CL to Calama based on the last 2 days. You can expect to find the cheapest price for the trip at $27 which is on 2025-08-13.

Usually PlussChile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Serena and Calama!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from La Serena to Calama.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from La Serena to Calama that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from La Serena to Calama, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to La Serena, CL by bus?

Bus from La Serena, CL to Calama

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting La Serena

Buses Leaving from La Serena

Buses Going to La Serena

Popular Buses Connecting Calama

Buses Leaving from Calama

Buses Going to Calama