Bus Tickets from Durham, NC, US to Buffalo, NY

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TodayAug 24
from $146
TomorrowAug 25
TueAug 26
WedAug 27
from $124
ThuAug 28
from $145
FriAug 29
SatAug 30
from $120
SunAug 31

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: August 27 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 27 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 27 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 28 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 27 at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 28 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Durham to Buffalo.

Bus
Average Price$104 - $299Average Duration21h 35m
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$166 - $388Average Duration1d 6h
70kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Buffalo

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 21 hours 35 minutes and with fares starting at just $104, it presents an excellent value for a comfortable ride.

10bus per day
21h 35mAverage Duration
$104Cheapest ticket
19kgCO₂ emissions

Bus Durham, NC, US to Buffalo, NY: Trip Overview

Average ticket price$164
Average bus trip duration21h 35m
Number of daily buses10
Earliest bus departure1:20am
Distance475 miles (766 km)
Latest bus departure9:15pm

Durham to Buffalo Bus

With Busbud, comparing and booking tickets for a bus from Durham to Buffalo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Durham to Buffalo will be provided by the most trusted bus companies.

Discover how much the bus trip from Durham to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Durham, NC, US - Buffalo, NY

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/22
$153
08/23
$133
Today
$137
08/25
No data
08/26
No data
08/27
$119
08/28
$137
08/29
$102
busbud logoThe cheapest trip from Durham, NC, US to Buffalo, NY was searched and found on Aug 29, 2025 with a price of $102

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Buffalo, NY, as early as possible.

You can expect to pay from $102 to $188 for a bus ticket from Durham, NC, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-08-29.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Durham to Buffalo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Durham to Buffalo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Durham to Buffalo will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Durham to Buffalo, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Durham, NC, US to Buffalo, NY?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham, NC, US by bus?

Bus from Buffalo, NY to Durham, NC, US

You can also go to Buffalo, NY by train

Train from Durham, NC, US to Buffalo, NY

Why choose Busbud?

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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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