Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Wilmington Bus Station | Durham Greyhound Bus Station | CheapestFastest | |||||
 | Wilmington Bus Station | Durham Greyhound Bus Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Newark (DE) | Durham Greyhound Bus Station | No tags | |||||
 | Newark (DE) | Durham Greyhound Bus Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Delaware Rest Stop S | Durham Greyhound Bus Station | No tags |
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Compare 2 ways to go from Wilmington to Durham
Busbud recommends taking the bus from Wilmington to DurhamAmong the sustainable travel choices, the bus stands out as a good way to reach Durham. The journey takes about 11 hours 5 minutes, and with fares starting at just US$53, it presents an excellent value for a comfortable ride.
Bus Wilmington, DE to Durham, NC, US: Trip Overview
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Wilmington to Durham Bus
With Busbud, comparing and booking tickets for a bus from Wilmington to Durham is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Wilmington to Durham will be provided by the most trusted bus companies.
Discover how much the bus trip from Wilmington to Durham will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Wilmington and Durham?
Frequently asked questions on the trip Wilmington, DE - Durham, NC, US
What is the travel distance from Wilmington to Durham?
The distance between Wilmington and Durham is around 509 km (316 miles).
What are the departure and arrival locations for buses traveling from Wilmington to Durham?
Buses traveling this route start their trip at Wilmington Bus Station, in Wilmington, and end it at Durham Greyhound Bus Station, in Durham.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Durham, NC, US was searched and found on Aug 28, 2025 with a price of US$49To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Durham, NC, US, as early as possible.
You can expect to pay from US$49 to US$78 for a bus ticket from Wilmington, DE to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$49 which is on 2025-08-28.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Wilmington to Durham.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Wilmington to Durham, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Wilmington to Durham will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to Durham while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
What's the cheapest way to go from Wilmington, DE to Durham, NC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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