Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Newark (DE) | 4565 Gaynor Ave, North Charleston | Cheapest | |||||
Greyhound Lines, Inc. + FlixBus | Wilmington Bus Station | 4565 Gaynor Ave, North Charleston | Fastest | |||||
Greyhound Lines, Inc. + FlixBus | Wilmington Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Wilmington Bus Station | 4565 Gaynor Ave, North Charleston | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Newark (DE) | 4565 Gaynor Ave, North Charleston | No tags |
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Compare 2 ways to go from Wilmington to Charleston
Busbud recommends taking the train from Wilmington to CharlestonAmong the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 11 hours 39 minutes, and with fares starting at just US$93, it presents an excellent value for a comfortable ride.
Bus Wilmington, DE to Charleston, SC, US: Trip Overview
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Wilmington to Charleston Bus
Busbud helps you find a bus from Wilmington to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Wilmington to Charleston.
Whether it is cheap bus tickets or more luxurious buses going to Charleston from Wilmington, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Wilmington and Charleston?
Frequently asked questions on the trip Wilmington, DE - Charleston, SC, US
What is the distance between Wilmington and Charleston?
Wilmington and Charleston are 868 km (538 miles) apart.
What are the departure and arrival locations for buses traveling from Wilmington to Charleston?
Buses departing from Wilmington Bus Station in Wilmington will take you to Charleston Bus Station in Charleston.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Charleston, SC, US was searched and found on Sep 4, 2025 with a price of US$79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Charleston, SC, US, as early as possible.
You can expect to pay from US$79 to US$135 for a bus ticket from Wilmington, DE to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$79 which is on 2025-09-04.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Charleston!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Wilmington to Charleston.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wilmington to Charleston.
Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to Charleston while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Wilmington, DE to Charleston, SC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Wilmington
Buses Leaving from Wilmington
- Bus from Wilmington to Wilmington
- Bus Wilmington - Myrtle Beach
- Wilmington - Philadelphia
- Bus from Wilmington to Charleston
- Bus Wilmington - Charleston
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- Bus Wilmington - Richmond
- Wilmington - Washington
- Bus from Wilmington to Dover
- Bus Wilmington - Newark
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- Bus from Wilmington to Atlanta
- Bus Wilmington - New Carrollton
- Wilmington - Aberdeen
Buses Going to Wilmington
- Bus from Wilmington to Wilmington
- Bus Corning - Wilmington
- Atlanta - Wilmington
- Bus from Chicago to Wilmington
- Bus Pittsburgh - Wilmington
- Raleigh - Wilmington
- Bus from New York City to Wilmington
- Bus Reading - Wilmington
- Washington - Wilmington
- Bus from Bridgeport to Wilmington
- Bus State College - Wilmington
- Baltimore - Wilmington
- Bus from Springfield to Wilmington
- Bus Boston - Wilmington
- Philadelphia - Wilmington
Popular Buses Connecting Charleston
Buses Leaving from Charleston
- Bus from Charleston to Baltimore
- Bus Charleston - Tulsa
- Charleston - Atlanta
- Bus from Charleston to Fort Worth
- Bus Charleston - Miami
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- Bus Charleston - Orlando
- Charleston - Springfield
- Bus from Charleston to Las Vegas
- Bus Charleston - Wilson
- Charleston - Providence
- Bus from Charleston to Raleigh
- Bus Charleston - Greensboro
- Charleston - Greenville
Buses Going to Charleston
- Bus from Baltimore to Charleston
- Bus Boston - Charleston
- Greenville - Charleston
- Bus from Raleigh to Charleston
- Bus Nashville - Charleston
- Los Angeles - Charleston
- Bus from Buffalo to Charleston
- Bus Savannah - Charleston
- Orlando - Charleston
- Bus from Austin to Charleston
- Bus Philadelphia - Charleston
- Spartanburg - Charleston
- Bus from Las Vegas to Charleston
- Bus Charlotte - Charleston
- Bangor - Charleston
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Albany - New York City
- Bus from Los Angeles to San Francisco
- Bus Baton Rouge - New Orleans
- Miami - Orlando
- Bus from Los Angeles to San Diego
- Bus Las Vegas - Los Angeles
- Atlanta - Savannah