Cheap buses leaving tomorrow
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: August 27 atDeparture city: TupeloDeparture location: Tupelo (Brothers Quick Stop)Arrival time: August 28 atDestination city: St. LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - This trip is recommended because it is the: Fastest
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Bus Tupelo to St. Louis: Trip Overview
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Based on 87205 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$69
Tupelo to St. Louis Bus
Busbud helps you find a bus from Tupelo to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Tupelo to St. Louis from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from Tupelo to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions on the trip Tupelo - St. Louis
What is the distance between Tupelo and St. Louis?
The distance covered from Tupelo to St. Louis is 508 km (315 miles).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to St. Louis was searched and found on Aug 28, 2025 with a price of US$61To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to St. Louis, as early as possible.
You can expect to pay from US$61 to US$88 for a bus ticket from Tupelo to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$61 which is on 2025-08-28.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tupelo and St. Louis!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tupelo to St. Louis, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Tupelo to St. Louis that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Tupelo to St. Louis while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top travelled bus routes
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