Bus Tickets from Spartanburg to St. Louis

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TodayAug 26
from $78
TomorrowAug 27
from $80
ThuAug 28
FriAug 29
SatAug 30
SunAug 31
from $89
MonSep 1
from $125
TueSep 2

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: August 27 at
    Departure city: Spartanburg
    Departure location: Spartanburg
    Arrival time: August 27 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Spartanburg
    Departure location: Spartanburg
    Arrival time: August 28 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Spartanburg
    Departure location: Spartanburg
    Arrival time: August 28 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Spartanburg
    Departure location: Spartanburg
    Arrival time: August 28 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Spartanburg to St. Louis: Trip Overview

Average ticket price$105
Average bus trip duration17h 35m
Number of daily buses4
Earliest bus departure6:05am
Distance517 miles (833 km)
Latest bus departure9:00pm

Spartanburg to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Spartanburg to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Spartanburg to St. Louis.

Discover how much the bus trip from Spartanburg to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Spartanburg - St. Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/24
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08/25
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Today
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08/27
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08/28
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08/29
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08/30
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08/31
$143
busbud logoThe cheapest trip from Spartanburg to St. Louis was searched and found on Aug 31, 2025 with a price of $143

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to St. Louis, as early as possible.

You can expect to pay from $143 to $143 for a bus ticket from Spartanburg to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $143 which is on 2025-08-31.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Spartanburg to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Spartanburg to St. Louis.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Spartanburg to St. Louis will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Spartanburg to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to Spartanburg by bus?

Bus from St. Louis to Spartanburg

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