Busbud recommends taking the train from Chicago to St. Louis
Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 5 hours 1 minute and with fares starting at just $30, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Amtrak Chicago St. Louis recent customer reviews
My trip experience was very quiet and smooth. I was in comfort and had plenty of space where I could relax and get some sleep. My trip was 4 1/2 hours.
4 out of 5 stars
Rosemarie H.
Everything was fine, senior customer assistance, smooth ride,nice seating all good
5 out of 5 stars
Samuel S.
The trip was the fastest available option. The train was very clean. I like how they announced for people to respect others and keep noise down by using headphones etc. I believe there was Wi-Fi available, I didn’t need though.
It was a great Amtrak experience I had compared to my past Amtrak travels, I remember from more than 2-3 years back. The food was also better than I remembered.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Amtrak Chicago St. Louis recent customer reviews
My trip experience was very quiet and smooth. I was in comfort and had plenty of space where I could relax and get some sleep. My trip was 4 1/2 hours.
4 out of 5 stars
Rosemarie H.
Everything was fine, senior customer assistance, smooth ride,nice seating all good
5 out of 5 stars
Samuel S.
The trip was the fastest available option. The train was very clean. I like how they announced for people to respect others and keep noise down by using headphones etc. I believe there was Wi-Fi available, I didn’t need though.
It was a great Amtrak experience I had compared to my past Amtrak travels, I remember from more than 2-3 years back. The food was also better than I remembered.
Based on 20 reviews, the company was rated 4.2 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Burlington Trailways ticket prices on this trip start at $182
Amtrak Chicago St. Louis recent customer reviews
My trip experience was very quiet and smooth. I was in comfort and had plenty of space where I could relax and get some sleep. My trip was 4 1/2 hours.
4 out of 5 stars
Rosemarie H.
Everything was fine, senior customer assistance, smooth ride,nice seating all good
5 out of 5 stars
Samuel S.
The trip was the fastest available option. The train was very clean. I like how they announced for people to respect others and keep noise down by using headphones etc. I believe there was Wi-Fi available, I didn’t need though.
It was a great Amtrak experience I had compared to my past Amtrak travels, I remember from more than 2-3 years back. The food was also better than I remembered.
Customers have shared positive experiences regarding their recent trips. They appreciated the quiet and smooth rides, comfortable seating with ample space to relax or sleep, and efficient senior customer assistance. Additionally, travelers noted that the train was very clean and enjoyed improved food quality compared to previous journeys.
Amtrak Chicago St. Louis recent customer reviews
My trip experience was very quiet and smooth. I was in comfort and had plenty of space where I could relax and get some sleep. My trip was 4 1/2 hours.
4 out of 5 stars
Rosemarie H.
Everything was fine, senior customer assistance, smooth ride,nice seating all good
5 out of 5 stars
Samuel S.
The trip was the fastest available option. The train was very clean. I like how they announced for people to respect others and keep noise down by using headphones etc. I believe there was Wi-Fi available, I didn’t need though.
It was a great Amtrak experience I had compared to my past Amtrak travels, I remember from more than 2-3 years back. The food was also better than I remembered.
With Busbud, comparing and booking tickets for a bus from Chicago to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Chicago to St. Louis from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Chicago to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Chicago and St. Louis?
Frequently asked questions for your trip Chicago - St. Louis
What is the travel distance from Chicago to St. Louis?
Chicago and St. Louis are 260 miles (419 km) apart.
What are the departure and arrival stations when taking the bus from Chicago to St. Louis?
The majority of buses traveling from Chicago to St. Louis start their journey at Downtown Greyhound Station and wind up at Gateway Station. These are the most popular pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in St. Louis?
Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are Missouri Botanical Garden, Saint Louis Science Center, St. Louis Cardinals, Old St. Louis County Courthouse and Lumière Place.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/21
$79
08/22
$88
Today
$68
08/24
$47
08/25
$38
08/26
$36
08/27
$36
08/28
$37
The cheapest trip from Chicago to St. Louis was searched and found on Aug 26, 2025 with a price of $36
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to St. Louis, as early as possible.
You can expect to pay from $36 to $123 for a bus ticket from Chicago to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2025-08-26.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Chicago to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to St. Louis, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to St. Louis that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to St. Louis.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
Busbud recommends taking the train from Chicago to St. Louis
The cheapest trip from Chicago to St. Louis was searched and found on Aug 26, 2025 with a price of $36
