Bus Tickets from Louisville to Panama City, US

Next departures

Next departures for Louisville to Panama City on August 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Louisville, KY
Panama City Beach StationCheapest
Greyhound Lines, Inc.
Louisville, KY
Panama City Beach StationFastest
Greyhound Lines, Inc.
Louisville, KY
Panama City Beach StationNo tags

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Bus Louisville to Panama City, US: Trip Overview

Average ticket price$101
Average bus trip duration23h 10m
Number of daily buses4
Earliest bus departure6:00am
Distance556 miles (896 km)
Latest bus departure10:55pm

Louisville to Panama City Bus

Busbud helps you find a bus from Louisville to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Louisville to Panama City will be provided by the most trusted bus companies.

Discover how much the bus trip from Louisville to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Louisville - Panama City, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/27
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08/28
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Today
$113
08/30
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08/31
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09/01
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busbud logoThe cheapest trip from Louisville to Panama City, US was searched and found on Aug 29, 2025 with a price of $113

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Panama City, US, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Louisville and Panama City!

Much more than a mere vehicle taking you from Louisville to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Louisville to Panama City will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Louisville to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Louisville by bus?

Bus from Panama City, US to Louisville

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