Busbud recommends taking the train from La Crosse to Milwaukee
Among the sustainable travel choices, the train stands out as the good way to reach Milwaukee. The journey takes about 3 hours 38 minutes and with fares starting at just $27, it presents an excellent value for a comfortable ride.
Traveling with Megabus from La Crosse to Milwaukee is an affordable and reliable way to reach your destination. The company provides amenities like comfortable seats and free Wi-Fi (on most buses), ensuring a comfortable journey. Discover an easy and budget-friendly travel option to Milwaukee with Megabus. Tickets start at just $46, with an average price of around $51, making it an accessible choice for travelers.
Jefferson Lines La Crosse Milwaukee recent customer reviews
confusing instructions to where the bus would pick me up, made me miss my bus. awful return exchange policy, so i cant do anything about it
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Jefferson Lines La Crosse Milwaukee recent customer reviews
confusing instructions to where the bus would pick me up, made me miss my bus. awful return exchange policy, so i cant do anything about it
Based on 5413 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $49
Jefferson Lines La Crosse Milwaukee recent customer reviews
confusing instructions to where the bus would pick me up, made me miss my bus. awful return exchange policy, so i cant do anything about it
Busbud helps you find a bus from La Crosse to Milwaukee. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from La Crosse to Milwaukee will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Milwaukee from La Crosse, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip La Crosse, WI - Milwaukee
What is the distance between La Crosse and Milwaukee?
La Crosse and Milwaukee are 176 miles (284 km) apart.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/20
$43
08/21
$39
Today
$39
08/23
$43
08/24
$39
08/25
$43
08/26
$43
08/27
$43
The cheapest trip from La Crosse, WI to Milwaukee was searched and found on Aug 21, 2025 with a price of $39
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Crosse, WI to Milwaukee, as early as possible.
You can expect to pay from $39 to $54 for a bus ticket from La Crosse, WI to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at $39 which is on 2025-08-24.
Usually Megabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Crosse and Milwaukee!
Much more than a mere vehicle taking you from La Crosse to Milwaukee, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Crosse to Milwaukee.
Make a music playlist for your bus ride from La Crosse to Milwaukee, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from La Crosse, WI to Milwaukee?
The bus is the cheapest travel choice for this destination
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
Busbud recommends taking the train from La Crosse to Milwaukee
The cheapest trip from La Crosse, WI to Milwaukee was searched and found on Aug 21, 2025 with a price of $39
The bus is the cheapest travel choice for this destination
