Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Downtown Gray & Smith | Knoxville Bus Station | Cheapest | |||||
 | Houston Bus Station | Knoxville Bus Station | Fastest | |||||
| Houston Bus Station | Knoxville Bus Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Downtown Gray & Smith | Knoxville Bus Station | No tags | |||||
Valley Transit + Greyhound Lines, Inc. | Hillcroft Ave & Southwest Freeway | Knoxville Bus Station | No tags |
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Bus Houston, US to Knoxville, TN: Trip Overview
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Houston to Knoxville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Houston to Knoxville.
Bus service from Houston to Knoxville will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Knoxville from Houston, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Houston and Knoxville?
Frequently asked questions for your trip Houston, US - Knoxville, TN
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to Knoxville, TN was searched and found on Sep 8, 2025 with a price of $98To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Knoxville, TN, as early as possible.
You can expect to pay from $98 to $150 for a bus ticket from Houston, US to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $98 which is on 2025-09-08.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Houston to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Houston to Knoxville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Houston to Knoxville.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Houston to Knoxville.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Houston
Buses Leaving from Houston
- Bus from Houston to Lamar
- Bus Houston - Marathon
- Houston - Pompano Beach
- Bus from Houston to Orlando
- Bus Houston - Hamilton
- Houston - San Diego
- Bus from Houston to New Orleans
- Bus Houston - Fort Worth
- Houston - Atlanta
- Bus from Houston to New York City
- Bus Houston - College Station
- Houston - Miami
- Bus from Houston to McAllen
- Bus Houston - Little Rock
- Houston - Chicago
Buses Going to Houston
- Bus from Cypress to Houston
- Bus Atlanta - Houston
- Katy - Houston
- Bus from New Orleans to Houston
- Bus Sunnyside - Houston
- Denver - Houston
- Bus from San Antonio to Houston
- Bus Fort Worth - Houston
- New York City - Houston
- Bus from McAllen to Houston
- Bus Laredo - Houston
- San Marcos - Houston
- Bus from El Paso to Houston
- Bus Baton Rouge - Houston
- Frisco - Houston
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Orlando
- Bus Knoxville - Chicago
- Knoxville - Greenville
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to New York City
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Miami
- Bus Knoxville - Jackson
- Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Detroit - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Cookeville - Knoxville
- Bus from Lexington to Knoxville
- Bus Dallas - Knoxville
- Dayton - Knoxville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Austin to Dallas
- Bus Seattle - Leavenworth
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from Houston to Austin
- Bus Dallas - San Antonio
- New York City - Los Angeles