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One passenger / one way
- Departure time: August 25 atDeparture city: FlorenceDeparture location: Florence Bus StationArrival time: August 25 atDestination city: GainesvilleDestination location: Rosa Parks StationOperated by: FlixBus
Vehicle: BusDuration: - Departure time: August 22 atDeparture city: FlorenceDeparture location: Florence, SCArrival time: August 22 atDestination city: GainesvilleDestination location: Rosa Parks StationOperated by: FlixBusVehicle: BusDuration:
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Compare 2 ways to go from Florence to Gainesville.
Busbud recommends taking the bus from Florence to GainesvilleAmong the sustainable travel choices, the bus stands out as the good way to reach Gainesville. The journey takes about 8 hours 30 minutes and with fares starting at just $56, it presents an excellent value for a comfortable ride.
Bus Florence, SC, US to Gainesville, FL: Trip Overview
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Florence to Gainesville Bus
With Busbud, comparing and booking tickets for a bus from Florence to Gainesville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Florence to Gainesville from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Florence to Gainesville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Florence and Gainesville?
Frequently asked questions for your trip Florence, SC, US - Gainesville, FL
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Gainesville, FL was searched and found on Aug 22, 2025 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Gainesville, FL, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Florence to Gainesville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Gainesville, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Gainesville that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Gainesville.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
What's the cheapest way to go from Florence, SC, US to Gainesville, FL?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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