How far is Florence from Chicago?

About 684 miles (1102 km) separate Florence and Chicago.

What are the departure and arrival stations when taking the bus from Florence to Chicago?

Most of the buses traveling from Florence to Chicago leave from Florence Bus Station and arrive at Downtown Greyhound Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Chicago?

Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Willis Tower (Sears Tower), Museum of Science and Industry, Cloud Gate, Robie House and Lincoln Park Zoo.

Bus Florence to Chicago from $157 | Compare & Save up to 10%

TodayAug 11

from $111

TomorrowAug 12

WedAug 13

ThuAug 14

FriAug 15

SatAug 16

SunAug 17

from $136

MonAug 18

from $122

Cheap buses leaving Sunday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: August 17 at 5:45am
Departure city: Florence
Departure location: Florence, SC
Arrival time: August 18 at 8:15am
Destination city: Chicago
Destination location: Downtown Greyhound Station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 3h
This trip is recommended because it is: Fastest
Departure time: August 17 at 5:45am
Departure city: Florence
Departure location: Florence, SC
Arrival time: August 18 at 7:55am
Destination city: Chicago
Destination location: 537-517 W. Jackson Blvd
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 3h
Departure time: August 17 at 12:55pm
Departure city: Florence
Departure location: Bus station
Arrival time: August 18 at 3:15pm
Destination city: Chicago
Destination location: Downtown Greyhound Station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 3h
Departure time: August 17 at 4:15pm
Departure city: Florence
Departure location: Bus station
Arrival time: August 18 at 9:40pm
Destination city: Chicago
Destination location: Chicago 95Th & Dan Ryan
Operated by: FlixBus
Vehicle: BusDuration: 1d 6h
Departure time: August 17 at 4:15pm
Departure city: Florence
Departure location: Bus station
Arrival time: August 18 at 8:10pm
Destination city: Chicago
Destination location: Downtown Greyhound Station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 4h

Accepted payments

Compare 2 ways to go from Florence to Chicago.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$108 - $423	Average Duration1d 6h	CO₂ emissions 27kg CO₂e5 out of 5 stars	CheapestFastestMost eco-friendly
Train	Average Price$186 - $1,605	Average Duration1d 11h	CO₂ emissions 100kg CO₂e1 out of 5 stars

Busbud recommends taking the bus from Florence to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 6 hours 35 minutes and with fares starting at just $108, it presents an excellent value for a comfortable ride.

10bus per day

1d 6hAverage Duration

$108Cheapest ticket

27kgCO₂ emissions

Bus Florence, SC, US to Chicago: Trip Overview

Average ticket price$174

Average bus trip duration1d 6h

Number of daily buses10

Earliest bus departure12:05am

Distance681 miles (1097 km)

Latest bus departure4:15pm

Compare bus companies

FlixBus

3.5/59,982 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,168 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Florence to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Chicago.

We make sure you can find a bus service from Florence to Chicago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Florence to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in Florence and Chicago?

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Frequently asked questions for your trip Florence, SC, US - Chicago

How far is Florence from Chicago?
What are the departure and arrival stations when taking the bus from Florence to Chicago?
What are the best sights and things to do in Chicago?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/09

No data

08/10

$161

Today

$157

08/12

No data

08/13

No data

08/14

No data

08/15

No data

08/16

No data

The cheapest trip from Florence, SC, US to Chicago was searched and found on Aug 11, 2025 with a price of $157

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Chicago, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Chicago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Chicago.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Florence, SC, US to Chicago?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time1d 6h	Avg Price$174	Daily Departures10
Vehicle TypeTrain	Travel Time1d 11h	Avg Price$448	Daily Departures2

Will you be returning to Florence, SC, US by bus?

Bus from Florence, SC, US to Chicago

You can also go to Chicago by train

Train from Florence, SC, US to Chicago

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Bus Tickets from Florence, SC, US to Chicago

One passenger / one way

Cheap buses leaving Sunday

One passenger / one way

One passenger / one way

Compare 2 ways to go from Florence to Chicago.

Bus Florence, SC, US to Chicago: Trip Overview

Compare bus companies

Florence to Chicago Bus

Where are the popular stops in Florence and Chicago?

Frequently asked questions for your trip Florence, SC, US - Chicago

How far is Florence from Chicago?

What are the departure and arrival stations when taking the bus from Florence to Chicago?

What are the best sights and things to do in Chicago?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Florence, SC, US to Chicago?

Will you be returning to Florence, SC, US by bus?

You can also go to Chicago by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Florence

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Popular Buses Connecting Chicago

Buses Leaving from Chicago

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Popular routes in this country

Popular airport transfers