Busbud recommends taking the bus from Durham to Chicago
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 2 hours 25 minutes and with fares starting at just $100, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
With Busbud, comparing and booking tickets for a bus from Durham to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Chicago.
From cheap bus tickets to more luxurious buses traveling from Durham to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Durham and Chicago?
Frequently asked questions for your trip Durham, NC, US - Chicago
How far is Durham from Chicago?
The distance separating Durham and Chicago is 620 miles (999 km).
What are the departure and arrival stations when taking the bus from Durham to Chicago?
Most of the buses traveling from Durham to Chicago leave from Durham Greyhound Bus Station and arrive at Downtown Greyhound Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Lincoln Park Conservatory, Navy Pier, Brookfield Zoo, Auditorium Building and Theatre and Museum of Science and Industry.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/19
No data
08/20
$97
Today
$116
08/22
No data
08/23
$124
08/24
$143
08/25
$103
08/26
$100
The cheapest trip from Durham, NC, US to Chicago was searched and found on Aug 20, 2025 with a price of $97
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Chicago, as early as possible.
You can expect to pay from $97 to $193 for a bus ticket from Durham, NC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $100 which is on 2025-08-26.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Durham to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Durham to Chicago.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Durham to Chicago that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Durham, NC, US to Chicago?
The bus is the cheapest travel choice for this destination
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
Busbud recommends taking the bus from Durham to Chicago
The cheapest trip from Durham, NC, US to Chicago was searched and found on Aug 20, 2025 with a price of $97
The bus is the cheapest travel choice for this destination
