Find coaches from Milano to Syracuse

Find affordable coach tickets from Milano to Syracuse with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen journeys

One passenger / one way

  • Departure time: 1 May at
    Departure city: Milano
    Departure location: Via Luigi Cadorna
    Arrival time: 2 May at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 1 May at
    Departure city: Milano
    Departure location: Milan (Malpensa Aeroporto Terminal 1)
    Arrival time: 2 May at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 1 May at
    Departure city: Milano
    Departure location: Aeroporto Malpensa T2
    Arrival time: 2 May at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 1 May at
    Departure city: Milano
    Departure location: Terminal Bus di Lampugnano
    Arrival time: 2 May at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 1 May at
    Departure city: Milano
    Departure location: Milan (San Donato M3)
    Arrival time: 2 May at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to travel from Milano to Syracuse

Bus
Average priceUS$58 - US$154Average duration1d 3h
26kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$305 - US$305Average duration22h 41m
26kg CO₂e5 out of 5 stars
Carpool
Average priceUS$120 - US$120Average duration15h 40m
45kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Milano to Syracuse

Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just US$58, it presents an excellent value for a comfortable ride.

6bus per day
1d 3hAverage duration
US$58Cheapest ticket
26kgCO₂ emissions

Bus Milano to Syracuse: Trip Overview

Average ticket priceUS$100
Average bus trip duration1d 3h
Number of daily buses6
Earliest bus departure12:55
Distance656 miles
Latest bus departure21:30

Milano to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Milano to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Milano to Syracuse.

Discover how much the bus trip from Milano to Syracuse will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milano - Syracuse

  1. How far is Syracuse from Milano by coach?

    The journey from Milano to Syracuse by coach covers an approximate distance of 660 miles (1064 km).

  2. Is there a way to reach Syracuse from Milano without flying?

    To travel from Milano to Syracuse without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/09
US$86
04/09
US$55
Today
US$68
06/09
US$83
07/09
US$78
08/09
US$62
09/09
US$66
10/09
US$61
busbud logoThe cheapest trip from Milano to Syracuse was searched and found on 4 Sept 2025 with a price of US$55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Syracuse as early as possible.

You can expect to pay from US$55 to US$169 for a bus ticket from Milano to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$61, which is on 2025-09-10.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Milano to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Milano to Syracuse.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Milano to Syracuse will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Milano to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Milano to Syracuse?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milano by bus?

Bus from Syracuse to Milano

You can also go to Syracuse by train

Train from Milano to Syracuse

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Milano

Buses Leaving from Milano

Buses Going to Milano

Popular Buses Connecting Syracuse

Buses Leaving from Syracuse

Buses Going to Syracuse