Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Milan (San Donato M3) | Terminal Interbus | Cheapest | |||||
| Lampugnano bus station | Terminal Interbus | Fastest | |||||
| Lampugnano bus station | Terminal Interbus | No tags | |||||
| Lampugnano bus station | Terminal Interbus | No tags | |||||
| Milan (Assago M2) | Terminal Interbus | No tags |
Accepted payments
Compare 3 ways to go from Milano to Syracuse
| Average Price | Average Duration | CO₂ emissions | |||
|---|---|---|---|---|---|
| Average PriceUS$58 - US$219 | Average Duration1d 3h | 27kg CO₂e5 out of 5 stars | Cheapest | ||
| Average PriceUS$305 - US$305 | Average Duration22h 41m | 26kg CO₂e5 out of 5 stars | Most eco-friendly | ||
Carpool | Average PriceUS$120 - US$120 | Average Duration15h 40m | 45kg CO₂e4 out of 5 stars | Fastest |
Busbud recommends taking the bus from Milano to SyracuseAmong the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 1 day, 3 hours 10 minutes, and with fares starting at just US$58, it presents an excellent value for a comfortable ride.
Bus Milano to Syracuse: Trip Overview
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Based on 10339 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at US$58
Milano to Syracuse Bus
With Busbud, comparing and booking tickets for a bus from Milano to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Milano to Syracuse.
Discover how much the bus trip from Milano to Syracuse will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Milano and Syracuse?
Frequently asked questions on the trip Milano - Syracuse
How much does a bus ticket from Milano to Syracuse cost?
The bus ticket price from Milano to Syracuse starts at US$58. The best way to find cheap bus tickets from Milano to Syracuse is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Milano to Syracuse?
The average travel time between Milano and Syracuse is around 1d 3h, although the fastest bus will take about 20h 40m.This is the time it takes to travel the 1064 km that separates the two cities.
How many daily bus connections are there between Milano and Syracuse?
The number of buses from Milano to Syracuse can differ depending on the day of the week. On average, there are 6 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Milano to Syracuse by comparing and selecting the bus that fits you travel style and budget on Busbud.
Which bus companies travel from Milano to Syracuse?
When taking the bus from Milano to Syracuse, you can travel comfortably and safely with FlixBus.
What are the departure and arrival stations when taking the bus from Milano to Syracuse?
Buses travelling between Milano and Syracuse leave from Lampugnano or Linate Airport and arrive at Fermata dell'autobus Siracusa, Siracusa, Siracusa - Terminal Bus (Stazione FS).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Syracuse was searched and found on Sep 4, 2025 with a price of US$55To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Syracuse, as early as possible.
You can expect to pay from US$55 to US$169 for a bus ticket from Milano to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$55 which is on 2025-09-04.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Milano to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Milano to Syracuse.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milano to Syracuse will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Milano to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Milano to Syracuse?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
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Popular Buses Connecting Milano
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Buses Going to Syracuse
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Popular routes in this country
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