Find coaches from Boston, MA, US to Florence, SC, US

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Today25 Aug
Tomorrow26 Aug
from US$83
Wed27 Aug
from US$72
Thu28 Aug
from US$123
Fri29 Aug
Sat30 Aug
Sun31 Aug
Mon1 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 26 August at
    Departure city: Boston
    Departure location: 151 Steel Pl, Cambridge
    Arrival time: 27 August at
    Destination city: Florence
    Destination location: Bus station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 26 August at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: 27 August at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 August at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: 27 August at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 August at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: 27 August at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 August at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: 28 August at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Boston to Florence

Average priceUS$83 - US$203Average duration22h 30m
30kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average priceUS$142 - US$779Average duration18h 52m
108kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Boston to Florence

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 22 hours 30 minutes and with fares starting at just US$83, it presents an excellent value for a comfortable ride.

5bus per day
22h 30mAverage duration
US$83Cheapest ticket
30kgCO₂ emissions

Bus Boston, MA, US to Florence, SC, US: Trip Overview

Average ticket priceUS$131
Average bus trip duration22h 30m
Number of daily buses5
Earliest bus departure01:30
Distance733 miles
Latest bus departure22:00

Boston to Florence Bus

With Busbud, comparing and booking tickets for a bus from Boston to Florence is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Boston to Florence.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Boston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Boston, MA, US - Florence, SC, US

  1. How far is Florence from Boston by coach?

    The distance between Boston and Florence by coach is approximately 729 miles (1176 km).

  2. Is there a way to reach Florence from Boston without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/08
US$133
24/08
US$125
Today
US$141
26/08
No data
27/08
No data
28/08
US$172
29/08
US$162
30/08
No data
busbud logoThe cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on 24 Aug 2025 with a price of US$125

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US as early as possible.

You can expect to pay from US$125 to US$172 for a bus ticket from Boston, MA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$162, which is on 2025-08-29.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Boston to Florence.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Boston to Florence.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Boston to Florence.

Make a music playlist for your bus ride from Boston to Florence, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Boston, MA, US to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Boston, MA, US by bus?

Bus from Florence, SC, US to Boston, MA, US

You can also go to Florence, SC, US by train

Train from Boston, MA, US to Florence, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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