Bus Tickets from Tupelo to Columbia, MO

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Previously seen trips

One passenger / one way

  • Departure time: August 17 at
    Departure city: Tupelo
    Departure location: Tupelo (Brothers Quick Stop)
    Arrival time: August 18 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: August 17 at
    Departure city: Tupelo
    Departure location: Tupelo (Brothers Quick Stop)
    Arrival time: August 17 at
    Destination city: Columbia
    Destination location: Midway Truck Plaza Bus Stop
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

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Bus Tupelo to Columbia, MO: Trip Overview

Average Ticket PriceUS$86
Average Bus Trip Duration13h 20m
Number of daily buses2
Earliest bus departure5:35am
Distance624 km
Latest bus departure9:35pm

Tupelo to Columbia Bus

Busbud helps you find a bus from Tupelo to Columbia. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Tupelo to Columbia from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Tupelo to Columbia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Tupelo - Columbia, MO

  1. How far is Tupelo from Columbia?

    The distance covered from Tupelo to Columbia is 619 km (384 miles).

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-17
US$89
08-18
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08-20
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08-21
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busbud logoThe cheapest trip from Tupelo to Columbia, MO was searched and found on Aug 17, 2025 with a price of US$89

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Columbia, MO, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tupelo and Columbia!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tupelo to Columbia, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Tupelo to Columbia that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Tupelo to Columbia, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Tupelo by bus?

Bus from Columbia, MO to Tupelo

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