Bus Tickets from Pittsburgh to Durham, NC, US

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TodaySep 3
TomorrowSep 4
FriSep 5
from US$67
SatSep 6
SunSep 7
from US$68
MonSep 8
from US$79
TueSep 9
from US$79
WedSep 10

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 5 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: September 6 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 5 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: September 6 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: September 5 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: September 5 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: September 5 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: September 6 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Pittsburgh to Durham

Bus
Average PriceUS$67 - US$162Average Duration15h
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$227 - US$274Average Duration1d 4h
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Pittsburgh to Durham

Among the sustainable travel choices, the bus stands out as a good way to reach Durham. The journey takes about 15 hours, and with fares starting at just US$67, it presents an excellent value for a comfortable ride.

3bus per day
15hAverage Duration
US$67Cheapest ticket
13kgCO₂ emissions

Bus Pittsburgh to Durham, NC, US: Trip Overview

Average Ticket PriceUS$90
Average Bus Trip Duration15h
Number of daily buses3
Earliest bus departure12:55am
Distance504 km
Latest bus departure11:10pm

Pittsburgh to Durham Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Pittsburgh to Durham.

We make it our job to connect you with the most dependable bus companies that cover bus service from Pittsburgh to Durham.

From cheap bus tickets to more luxurious buses travelling from Pittsburgh to Durham, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Pittsburgh - Durham, NC, US

  1. How far is Pittsburgh from Durham?

    Pittsburgh and Durham are 505 km (313 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Pittsburgh to Durham?

    Buses departing from Intermodal Station in Pittsburgh will take you to Durham Greyhound Bus Station in Durham.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-01
US$83
09-02
No data
Today
No data
09-04
No data
09-05
US$60
09-06
No data
09-07
US$64
09-08
US$72
busbud logoThe cheapest trip from Pittsburgh to Durham, NC, US was searched and found on Sep 5, 2025 with a price of US$60

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Durham, NC, US, as early as possible.

You can expect to pay from US$60 to US$117 for a bus ticket from Pittsburgh to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$60 which is on 2025-09-05.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Pittsburgh to Durham but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Pittsburgh to Durham.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pittsburgh to Durham that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Pittsburgh to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Pittsburgh to Durham, NC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Pittsburgh by bus?

Bus from Durham, NC, US to Pittsburgh

You can also go to Durham, NC, US by train

Train from Pittsburgh to Durham, NC, US

Why choose Busbud?

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