Bus Tickets from Florence, SC, US to Boston, MA, US

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TodayAug 28
TomorrowAug 29
SatAug 30
SunAug 31
MonSep 1
from US$150
TueSep 2
from US$99
WedSep 3
from US$88
ThuSep 4

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 1 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: September 2 at
    Destination city: Boston
    Destination location: 151 Steel Pl, Cambridge
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 1 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: September 1 at
    Destination city: Boston
    Destination location: Boston (South Station)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 1 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: September 2 at
    Destination city: Boston
    Destination location: Boston (South Station)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 1 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: September 1 at
    Destination city: Boston
    Destination location: Boston (South Station)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 1 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: September 2 at
    Destination city: Boston
    Destination location: Brookline
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Florence to Boston

Bus
Average PriceUS$78 - US$398Average Duration1d 3h
30kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$164 - US$572Average Duration22h 48m
107kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Florence to Boston

Among the sustainable travel choices, the bus stands out as a good way to reach Boston. The journey takes about 1 day, 3 hours 5 minutes, and with fares starting at just US$78, it presents an excellent value for a comfortable ride.

5bus per day
1d 3hAverage Duration
US$78Cheapest ticket
30kgCO₂ emissions

Bus Florence, SC, US to Boston, MA, US: Trip Overview

Average Ticket PriceUS$145
Average Bus Trip Duration1d 3h
Number of daily buses5
Earliest bus departure12:05am
Distance1182 km
Latest bus departure4:15pm

Florence to Boston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Boston.

We make sure you can find a bus service from Florence to Boston from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Florence to Boston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Florence, SC, US - Boston, MA, US

  1. What is the distance between Florence and Boston?

    It's about 1176 km (729 miles) from Florence to Boston.

  2. What are the departure and arrival locations for buses traveling from Florence to Boston?

    Buses departing from Florence Bus Station in Florence will take you to Back Bay Station in Boston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-26
US$130
08-27
US$127
Today
No data
08-29
No data
08-30
No data
08-31
No data
09-01
No data
09-02
US$113
busbud logoThe cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Sep 2, 2025 with a price of US$113

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from US$113 to US$130 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$113 which is on 2025-09-02.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Boston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Florence to Boston, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Boston that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Boston while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Florence, SC, US to Boston, MA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Boston, MA, US to Florence, SC, US

You can also go to Boston, MA, US by train

Train from Florence, SC, US to Boston, MA, US

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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