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- This trip is recommended because it is: Cheapest + Fastest
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Compare 2 ways to go from Prague to Brussels.
Busbud recommends taking the train from Prague to BrusselsAmong the sustainable travel choices, the train stands out as the good way to reach Brussels. The journey takes about 13 hours 3 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.
Train Prague to Brussels: Trip Overview
Please note, this information is subject to change.
Prague to Brussels Train
With Busbud, comparing and booking tickets for a train from Prague to Brussels is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make sure you can find a train service from Prague to Brussels from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to Brussels from Prague, we help you find what you're looking for based on how much of a budget you have.
Where are the popular train stations and stops in Prague and Brussels?
Frequently asked questions for your trip Prague - Brussels
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Brussels was searched and found on Aug 12, 2025 with a price of $119To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Brussels, as early as possible.
You can expect to pay from $119 to $1,496 for a train ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $264 which is on 2025-08-14.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Prague to Brussels is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Regional train? High-speed train? Whichever train to Brussels you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Prague and Brussels, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Make a music playlist for your train ride from Prague to Brussels, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
Top Traveled Train Routes
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Popular Trains Connecting Brussels
Trains Going to Brussels
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