Busbud recommends taking the bus from Tampa to Charleston
Among the sustainable travel choices, the bus stands out as the good way to reach Charleston. The journey takes about 16 hours and with fares starting at just $51, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 5413 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $76
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We make sure you can find a bus service from Tampa to Charleston from the most reliable bus companies operating this trip.
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Where are the popular stops in Tampa and Charleston?
Frequently asked questions for your trip Tampa - Charleston, SC, US
What is the distance between Tampa and Charleston?
About 366 miles (591 km) separate Tampa and Charleston.
What are the departure and arrival stations when taking the bus from Tampa to Charleston?
If you're headed to Charleston from Tampa, chances are that your bus will leave from Tampa 13th Avenue Bus Stop (McDonald's) and arrive at Charleston Bus Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Charleston?
Once in Charleston, you can start exploring the city and discover its surroundings. The top sights and things to do are Middleton Place, Splash Zone Waterpark At James Island County Park, Schooner Pride, Fort Sumter and Palmetto Carriage Tour.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/20
$57
08/21
$58
Today
$60
08/23
$62
08/24
$65
08/25
$65
08/26
$65
08/27
$67
The cheapest trip from Tampa to Charleston, SC, US was searched and found on Aug 20, 2025 with a price of $57
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Charleston, SC, US, as early as possible.
You can expect to pay from $57 to $475 for a bus ticket from Tampa to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $62 which is on 2025-08-23.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Tampa to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tampa to Charleston, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Tampa to Charleston will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Tampa to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
What's the cheapest way to go from Tampa to Charleston, SC, US?
The bus is the cheapest travel choice for this destination
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
Busbud recommends taking the bus from Tampa to Charleston
The cheapest trip from Tampa to Charleston, SC, US was searched and found on Aug 20, 2025 with a price of $57
The bus is the cheapest travel choice for this destination
