Bus Tickets from Syracuse, US to Winston-Salem

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Previously seen trips

One passenger / one way

  • Departure time: September 12 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: September 13 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 12 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: September 13 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 12 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: September 13 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: December 1 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: December 2 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: December 1 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: December 2 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Compare 2 ways to go from Syracuse to Winston-Salem.

Bus
Average Price$122 - $191Average Duration21h
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$252 - $252Average Duration1d 5h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Syracuse to Winston-Salem

Among the sustainable travel choices, the bus stands out as the good way to reach Winston-Salem. The journey takes about 21 hours and with fares starting at just $122, it presents an excellent value for a comfortable ride.

3bus per day
21hAverage Duration
$122Cheapest ticket
21kgCO₂ emissions

Bus Syracuse, US to Winston-Salem: Trip Overview

Average ticket price$169
Average bus trip duration21h
Number of daily buses3
Earliest bus departure9:25am
Distance528 miles (851 km)
Latest bus departure9:00pm

Syracuse to Winston-Salem Bus

Busbud helps you find a bus from Syracuse to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Syracuse to Winston-Salem from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Syracuse to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Syracuse, US - Winston-Salem

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/26
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08/27
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Today
$130
08/29
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08/30
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08/31
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09/01
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busbud logoThe cheapest trip from Syracuse, US to Winston-Salem was searched and found on Aug 28, 2025 with a price of $130

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Winston-Salem, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Syracuse and Winston-Salem!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to Winston-Salem, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Syracuse to Winston-Salem that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Syracuse to Winston-Salem.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Syracuse, US to Winston-Salem?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse, US by bus?

Bus from Winston-Salem to Syracuse, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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