Busbud recommends taking the train from San Luis Obispo to San Diego
Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 8 hours 52 minutes and with fares starting at just $65, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Amtrak San Luis Obispo San Diego recent customer reviews
Based on 5417 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $89
Amtrak San Luis Obispo San Diego recent customer reviews
With Busbud, comparing and booking tickets for a bus from San Luis Obispo to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from San Luis Obispo to San Diego.
Whether it is cheap bus tickets or more luxurious buses going to San Diego from San Luis Obispo, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in San Luis Obispo and San Diego?
Stops in San Luis Obispo
A - AMTRAK Station
1730 Santa Rosa St, San Luis Obispo, CA 93401, USAAMTRAK Station
Frequently asked questions for your trip San Luis Obispo - San Diego, CA, US
What is the distance between San Luis Obispo and San Diego?
The distance between the two cities is 264 miles (426 km).
What are the departure and arrival stations when taking the bus from San Luis Obispo to San Diego?
If you're headed to San Diego from San Luis Obispo, chances are that your bus will depart from AMTRAK Station and arrive at Mission Valley Sheraton. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in San Diego?
Once in San Diego, you can start exploring the city and discover its surroundings. The top sights and things to do are USS Midway Museum, Boat Tours in San Diego, La Jolla Cove, Botanical Building and Lily Pond and Sunset Cliffs Natural Park.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/21
$60
08/22
$68
Today
$68
08/24
$68
08/25
$37
08/26
$42
08/27
$38
08/28
$49
The cheapest trip from San Luis Obispo to San Diego, CA, US was searched and found on Aug 25, 2025 with a price of $37
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Diego, CA, US, as early as possible.
You can expect to pay from $37 to $99 for a bus ticket from San Luis Obispo to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $37 which is on 2025-08-25.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from San Luis Obispo to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Luis Obispo to San Diego.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Luis Obispo to San Diego.
Tune out to the fine sounds of your best music playlist on your bus trip from San Luis Obispo to San Diego while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.