Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Salisbury (Park & Ride) | Downtown Greyhound Station | Cheapest | |||||
 | BayRunner Shuttle | Chicago (Union Station), IL | Fastest | |||||
| BayRunner Shuttle | Chicago (Union Station), IL | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Salisbury (Park & Ride) | Downtown Greyhound Station | No tags | |||||
| BayRunner Shuttle | Chicago (Union Station), IL | No tags |
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Bus Salisbury, MD, US to Chicago: Trip Overview
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Salisbury to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Salisbury to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Salisbury to Chicago from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Salisbury to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Salisbury and Chicago?
Frequently asked questions for your trip Salisbury, MD, US - Chicago
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, MD, US to Chicago was searched and found on Aug 30, 2025 with a price of $237To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, MD, US to Chicago, as early as possible.
You can expect to pay from $237 to $704 for a bus ticket from Salisbury, MD, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $237 which is on 2025-08-30.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Salisbury to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Salisbury to Chicago, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Salisbury to Chicago that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Salisbury to Chicago.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top traveled bus routes
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Popular Buses Connecting Salisbury
Buses Leaving from Salisbury
- Bus from Salisbury to New Brunswick
- Bus Salisbury - Baltimore
- Salisbury - Boston
- Bus from Salisbury to Dover
- Bus Salisbury - St. Louis
- Salisbury - Washington
- Bus from Salisbury to New York City
- Bus Salisbury - Philadelphia
- Salisbury - Newark
- Bus from Salisbury to Wilmington
- Bus Salisbury - Aberdeen
- Salisbury - North East
- Bus from Salisbury to Hampton
- Bus Salisbury - Laurel
- Salisbury - Norfolk
Buses Going to Salisbury
- Bus from Salisbury to Salisbury
- Bus Burlington - Salisbury
- Hampton - Salisbury
- Bus from Charlotte to Salisbury
- Bus London - Salisbury
- Wilson - Salisbury
- Bus from New York City to Salisbury
- Bus Washington - Salisbury
- Baltimore - Salisbury
- Bus from Philadelphia to Salisbury
- Bus Newark - Salisbury
- Wilmington - Salisbury
- Bus from Boston to Salisbury
- Bus Norfolk - Salisbury
- Dover - Salisbury
Popular Buses Connecting Chicago
Buses Leaving from Chicago
- Bus from Chicago to Columbia
- Bus Chicago - Seattle
- Chicago - Orlando
- Bus from Chicago to Toronto
- Bus Chicago - Washington
- Chicago - Mexico City
- Bus from Chicago to Madison
- Bus Chicago - Indianapolis
- Chicago - Minneapolis
- Bus from Chicago to New York City
- Bus Chicago - Green Bay
- Chicago - Rockford
- Bus from Chicago to Milwaukee
- Bus Chicago - Champaign
- Chicago - Phoenix
Buses Going to Chicago
- Bus from Boston to Chicago
- Bus Toronto - Chicago
- Indianapolis - Chicago
- Bus from Atlanta to Chicago
- Bus Bridgeport - Chicago
- Auburn - Chicago
- Bus from Madison to Chicago
- Bus New York City - Chicago
- Green Bay - Chicago
- Bus from Lafayette to Chicago
- Bus Minneapolis - Chicago
- Milwaukee - Chicago
- Bus from Champaign to Chicago
- Bus Appleton - Chicago
- Bloomington - Chicago
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Seattle to Leavenworth
- Bus Austin - Dallas
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from New York City to Los Angeles
- Bus Dallas - San Antonio
- Houston - Austin