Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Liberty St SE | Chicago 95Th & Dan Ryan | Cheapest | |||||
 | Salem | Chicago (Union Station), IL | Fastest | |||||
| Salem | Chicago (Union Station), IL | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Liberty St SE | Downtown Greyhound Station | No tags | |||||
| Salem | Chicago (Union Station), IL | No tags |
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Compare 2 ways to go from Salem to Chicago.
Busbud recommends taking the bus from Salem to ChicagoAmong the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 3 days, 6 hours 10 minutes and with fares starting at just $234, it presents an excellent value for a comfortable ride.
Bus Salem, OR, US to Chicago: Trip Overview
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Salem to Chicago Bus
With Busbud, comparing and booking tickets for a bus from Salem to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Salem to Chicago.
Whether it is cheap bus tickets or more luxurious buses going to Chicago from Salem, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Salem, OR, US - Chicago
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salem, OR, US to Chicago was searched and found on Aug 27, 2025 with a price of $301To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salem, OR, US to Chicago, as early as possible.
You can expect to pay from $301 to $3,448 for a bus ticket from Salem, OR, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $301 which is on 2025-08-31.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Salem to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Salem to Chicago.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Salem to Chicago.
Tune out to the fine sounds of your best music playlist on your bus trip from Salem to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
What's the cheapest way to go from Salem, OR, US to Chicago?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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