Bus Tickets from Myrtle Beach to Wilmington, DE

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from $103

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: August 21 at
    Departure city: Myrtle Beach
    Departure location: Bus Station
    Arrival time: August 22 at
    Destination city: Wilmington
    Destination location: Wilmington Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 21 at
    Departure city: Myrtle Beach
    Departure location: Bus Station
    Arrival time: August 22 at
    Destination city: Wilmington
    Destination location: Newark (DE)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 21 at
    Departure city: Myrtle Beach
    Departure location: Bus Station
    Arrival time: August 22 at
    Destination city: Wilmington
    Destination location: Delaware Rest Stop S
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 21 at
    Departure city: Myrtle Beach
    Departure location: Bus Station
    Arrival time: August 22 at
    Destination city: Wilmington
    Destination location: Delaware Rest Stop S
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Myrtle Beach to Wilmington, DE: Trip Overview

Average ticket price$99
Average bus trip duration18h 30m
Number of daily buses2
Earliest bus departure12:45pm
Distance456 miles (735 km)

Myrtle Beach to Wilmington Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Myrtle Beach to Wilmington.

Bus service from Myrtle Beach to Wilmington will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Wilmington from Myrtle Beach, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Myrtle Beach - Wilmington, DE

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/12
$81
08/13
$79
Today
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08/15
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08/16
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busbud logoThe cheapest trip from Myrtle Beach to Wilmington, DE was searched and found on Aug 13, 2025 with a price of $79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Wilmington, DE, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Myrtle Beach to Wilmington but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Myrtle Beach to Wilmington, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Myrtle Beach to Wilmington.

Make a music playlist for your bus ride from Myrtle Beach to Wilmington, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Myrtle Beach by bus?

Bus from Myrtle Beach to Wilmington, DE

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