Bus Tickets from Milano to Palermo

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TodayAug 17
from $88
TomorrowAug 18
from $111
TueAug 19
from $117
WedAug 20
ThuAug 21
FriAug 22
SatAug 23
SunAug 24

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 18 at
    Departure city: Milano
    Departure location: Lampugnano bus station
    Arrival time: August 19 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 18 at
    Departure city: Milano
    Departure location: Milan San Donato Bus Station
    Arrival time: August 19 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: August 18 at
    Departure city: Milano
    Departure location: Lampugnano
    Arrival time: August 19 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: MarinoBus + MarinoBus
    MarinoBus + MarinoBus
    Vehicle: BusDuration:
  • Departure time: August 18 at
    Departure city: Milano
    Departure location: Lampugnano
    Arrival time: August 19 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: August 18 at
    Departure city: Milano
    Departure location: Lampugnano bus station
    Arrival time: August 19 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

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Compare 2 ways to go from Milano to Palermo.

Bus
Average Price$50 - $247Average Duration1d 1h
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average Price$74 - $141Average Duration16h 30m
37kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milano to Palermo

Among the sustainable travel choices, the carpool stands out as the good way to reach Palermo. The journey takes about 16 hours 30 minutes and with fares starting at just $74, it presents an excellent value for a comfortable ride.

1carpool per day
16h 30mAverage Duration
$74Cheapest ticket
37kgCO₂ emissions

Bus Milano to Palermo: Trip Overview

Average ticket price$121
Average bus trip duration1d 1h
Number of daily buses16
Earliest bus departure3:35am
Distance549 miles (885 km)
Latest bus departure11:50pm

Milano to Palermo Bus

Busbud helps you find a bus from Milano to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Milano to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Milano to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Milano - Palermo

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/15
$126
08/16
$92
Today
$84
08/18
$106
08/19
$106
08/20
$105
08/21
$103
08/22
$107
busbud logoThe cheapest trip from Milano to Palermo was searched and found on Aug 17, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo, as early as possible.

You can expect to pay from $84 to $268 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2025-08-21.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milano and Palermo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milano to Palermo, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milano to Palermo will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milano to Palermo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Milano by bus?

Bus from Milano to Palermo

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