Bus Tickets from Madrid to Santander

Next departures

Next departures for Madrid to Santander on August 24
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSA
Avenida de América Metro
Santander (Estacion de Autobuses)Cheapest
ALSA Supra
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)Fastest
ALSA Supra
Avenida de América Metro
Santander (Estacion de Autobuses)No tags
ALSA
Avenida de América Metro
Santander (Estacion de Autobuses)No tags
Flixbus
Madrid (South)
Santander (Estacion de Autobuses)No tags

Accepted payments

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Compare 3 ways to go from Madrid to Santander.

Bus
Average Price$51 - $178Average Duration5h 30m
8kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average Price$38 - $97Average Duration4h 21m
8kg CO₂e5 out of 5 stars
Fastest
Carpool
Average Price$20 - $63Average Duration4h 40m
14kg CO₂e4 out of 5 stars
Cheapest
busbud logoBusbud recommends carpooling from Madrid to Santander

Among the sustainable travel choices, the carpool stands out as the good way to reach Santander. The journey takes about 4 hours 40 minutes and with fares starting at just $20, it presents an excellent value for a comfortable ride.

46carpool per day
4h 40mAverage Duration
$20Cheapest ticket
14kgCO₂ emissions

Bus Madrid to Santander: Trip Overview

Average ticket price$54
Average bus trip duration5h 30m
Number of daily buses13
Earliest bus departure12:30am
Distance209 miles (336 km)
Latest bus departure11:30pm

Madrid to Santander Bus

With Busbud, comparing and booking tickets for a bus from Madrid to Santander is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Madrid to Santander.

Discover how much the bus trip from Madrid to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Madrid - Santander

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/21
$48
08/22
$48
Today
$47
08/24
$48
08/25
$47
08/26
$48
08/27
$44
08/28
$44
busbud logoThe cheapest trip from Madrid to Santander was searched and found on Aug 27, 2025 with a price of $44

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Santander, as early as possible.

You can expect to pay from $44 to $244 for a bus ticket from Madrid to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $44 which is on 2025-08-27.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Madrid to Santander.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Madrid to Santander.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Madrid to Santander will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Madrid to Santander.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Madrid by bus?

Bus from Santander to Madrid

You can also go to Santander by train

Train from Madrid to Santander

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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