Cheap buses leaving tomorrow
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: September 7 atDeparture city: KnoxvilleDeparture location: Knoxville Bus StationArrival time: September 8 atDestination city: SpartanburgDestination location: SpartanburgOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Accepted payments
Bus Knoxville, TN to Spartanburg: Trip Overview
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Knoxville to Spartanburg Bus
With Busbud, comparing and booking tickets for a bus from Knoxville to Spartanburg is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Knoxville to Spartanburg.
Whether it is cheap bus tickets or more luxurious buses going to Spartanburg from Knoxville, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Knoxville and Spartanburg?
Frequently asked questions for your trip Knoxville, TN - Spartanburg
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Spartanburg was searched and found on Sep 6, 2025 with a price of $49To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Spartanburg, as early as possible.
You can expect to pay from $49 to $57 for a bus ticket from Knoxville, TN to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at $53 which is on 2025-09-07.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Knoxville to Spartanburg.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Knoxville to Spartanburg.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Knoxville to Spartanburg.
Tune out to the fine sounds of your best music playlist on your bus trip from Knoxville to Spartanburg while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Marathon
- Knoxville - Lexington
- Bus from Knoxville to Chicago
- Bus Knoxville - Orlando
- Knoxville - Greenville
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to New York City
- Bus Knoxville - Washington
- Knoxville - Asheville
- Bus from Knoxville to Miami
- Bus Knoxville - Jackson
- Knoxville - Cincinnati
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Richmond - Knoxville
- Bus from Atlanta to Knoxville
- Bus Asheville - Knoxville
- New York City - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Cookeville - Knoxville
- Bus from Dallas to Knoxville
- Bus Lexington - Knoxville
- Dayton - Knoxville
Popular Buses Connecting Spartanburg
Buses Leaving from Spartanburg
- Bus from Spartanburg to Greenville
- Bus Spartanburg - Greenville
- Spartanburg - Charlotte
- Bus from Spartanburg to Atlanta
- Bus Spartanburg - Florence
- Spartanburg - Charleston
- Bus from Spartanburg to LaGrange
- Bus Spartanburg - Myrtle Beach
- Spartanburg - Raleigh
- Bus from Spartanburg to New York City
- Bus Spartanburg - Wilson
- Spartanburg - Charleston
- Bus from Spartanburg to Miami
- Bus Spartanburg - Orlando
- Spartanburg - Newark
Buses Going to Spartanburg
- Bus from Greenville to Spartanburg
- Bus Greenville - Spartanburg
- El Paso - Spartanburg
- Bus from Burlington to Spartanburg
- Bus Orlando - Spartanburg
- Asheville - Spartanburg
- Bus from Atlanta to Spartanburg
- Bus Charlotte - Spartanburg
- Lake City - Spartanburg
- Bus from New York City to Spartanburg
- Bus Charleston - Spartanburg
- Myrtle Beach - Spartanburg
- Bus from Jacksonville to Spartanburg
- Bus Savannah - Spartanburg
- Colonial Heights - Spartanburg
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Miami - Tampa
- Bus from Austin to Dallas
- Bus Seattle - Leavenworth
- Dallas - Austin
- Bus from Houston to San Antonio
- Bus Austin - Houston
- Orlando - Atlanta
- Bus from Dallas to San Antonio
- Bus Houston - Austin
- New York City - Los Angeles