Bus Tickets from Greenville, SC to Detroit, MI

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TodayAug 29
TomorrowAug 30
SunAug 31
MonSep 1
from $139
TueSep 2
WedSep 3
ThuSep 4
FriSep 5

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: September 1 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: September 2 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: September 1 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: September 2 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 1 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: September 2 at
    Destination city: Detroit
    Destination location: Detroit Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Greenville to Detroit.

Bus
Average Price$89 - $245Average Duration19h 10m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$445 - $656Average Duration1d 18h
76kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Detroit

Among the sustainable travel choices, the bus stands out as the good way to reach Detroit. The journey takes about 19 hours 10 minutes and with fares starting at just $89, it presents an excellent value for a comfortable ride.

2bus per day
19h 10mAverage Duration
$89Cheapest ticket
21kgCO₂ emissions

Bus Greenville, SC to Detroit, MI: Trip Overview

Average ticket price$122
Average bus trip duration19h 10m
Number of daily buses2
Earliest bus departure2:45pm
Distance519 miles (836 km)
Latest bus departure10:00pm

Greenville to Detroit Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Detroit is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Greenville to Detroit will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Greenville to Detroit, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Greenville, SC - Detroit, MI

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/27
$149
08/28
No data
Today
$122
08/30
No data
08/31
No data
09/01
$178
09/02
No data
09/03
No data
busbud logoThe cheapest trip from Greenville, SC to Detroit, MI was searched and found on Aug 29, 2025 with a price of $122

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Detroit, MI, as early as possible.

You can expect to pay from $122 to $178 for a bus ticket from Greenville, SC to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $178 which is on 2025-09-01.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Greenville to Detroit.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Greenville to Detroit, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Greenville to Detroit that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Detroit.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Greenville, SC to Detroit, MI?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Detroit, MI to Greenville, SC

You can also go to Detroit, MI by train

Train from Greenville, SC to Detroit, MI

Why choose Busbud?

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