Bus Tickets from Des Moines to Philadelphia, PA

Find affordable bus tickets from Des Moines to Philadelphia, PA with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayAug 23
TomorrowAug 24
MonAug 25
TueAug 26
from $166
WedAug 27
ThuAug 28
FriAug 29
SatAug 30

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: August 26 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 27 at
    Destination city: Philadelphia
    Destination location: 199 Spring Garden St.
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 26 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 27 at
    Destination city: Philadelphia
    Destination location: Cherry Hill Mall
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 26 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 27 at
    Destination city: Philadelphia
    Destination location: Camden (Walter Rand Transportation Center)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 26 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 28 at
    Destination city: Philadelphia
    Destination location: Philadelphia (Logan Square)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 26 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 27 at
    Destination city: Philadelphia
    Destination location: Frazer - 56-40 Matthews Rd
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Des Moines to Philadelphia, PA: Trip Overview

Average ticket price$235
Average bus trip duration1d 14h
Number of daily buses5
Earliest bus departure5:30am
Distance970 miles (1564 km)

Des Moines to Philadelphia Bus

With Busbud, comparing and booking tickets for a bus from Des Moines to Philadelphia is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Des Moines to Philadelphia from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Des Moines to Philadelphia, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Des Moines - Philadelphia, PA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/21
No data
08/22
No data
Today
No data
08/24
No data
08/25
No data
08/26
$159
08/27
No data
08/28
No data
busbud logoThe cheapest trip from Des Moines to Philadelphia, PA was searched and found on Aug 26, 2025 with a price of $159

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Philadelphia, PA, as early as possible.

You can expect to pay from $159 to $159 for a bus ticket from Des Moines to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $159 which is on 2025-08-26.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Des Moines to Philadelphia.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Philadelphia, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Philadelphia that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to Philadelphia while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Des Moines by bus?

Bus from Philadelphia, PA to Des Moines

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines

Popular Buses Connecting Philadelphia

Buses Leaving from Philadelphia

Buses Going to Philadelphia