Bus Tickets from Charlotte, NC to Buffalo, NY

Find affordable bus tickets from Charlotte, NC to Buffalo, NY with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayAug 31
from $233
TomorrowSep 1
from $162
TueSep 2
from $135
WedSep 3
from $123
ThuSep 4
from $130
FriSep 5
from $134
SatSep 6
from $129
SunSep 7

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: September 1 at
    Departure city: Charlotte
    Departure location: Charlotte Bus Station
    Arrival time: September 3 at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: September 1 at
    Departure city: Charlotte
    Departure location: Charlotte Bus Station
    Arrival time: September 2 at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 1 at
    Departure city: Charlotte
    Departure location: Charlotte Bus Station
    Arrival time: September 2 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: September 1 at
    Departure city: Charlotte
    Departure location: Charlotte Bus Station
    Arrival time: September 2 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 1 at
    Departure city: Charlotte
    Departure location: Charlotte Bus Station
    Arrival time: September 3 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Charlotte to Buffalo.

Bus
Average Price$110 - $292Average Duration23h 5m
22kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$168 - $411Average Duration1d 8h
79kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Charlotte to Buffalo

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 23 hours 5 minutes and with fares starting at just $110, it presents an excellent value for a comfortable ride.

19bus per day
23h 5mAverage Duration
$110Cheapest ticket
22kgCO₂ emissions

Bus Charlotte, NC to Buffalo, NY: Trip Overview

Average ticket price$142
Average bus trip duration23h 5m
Number of daily buses19
Earliest bus departure1:10am
Distance539 miles (868 km)
Latest bus departure11:59pm

Charlotte to Buffalo Bus

Busbud helps you find a bus from Charlotte to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Charlotte to Buffalo will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Charlotte to Buffalo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Charlotte, NC - Buffalo, NY

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/29
$213
08/30
$215
Today
$216
09/01
$154
09/02
$127
09/03
$115
09/04
$122
09/05
$126
busbud logoThe cheapest trip from Charlotte, NC to Buffalo, NY was searched and found on Sep 3, 2025 with a price of $115

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to Buffalo, NY, as early as possible.

You can expect to pay from $115 to $241 for a bus ticket from Charlotte, NC to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $115 which is on 2025-09-03.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Charlotte and Buffalo!

Much more than a mere vehicle taking you from Charlotte to Buffalo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Charlotte to Buffalo that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Charlotte to Buffalo while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Charlotte, NC to Buffalo, NY?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charlotte, NC by bus?

Bus from Buffalo, NY to Charlotte, NC

You can also go to Buffalo, NY by train

Train from Charlotte, NC to Buffalo, NY

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Charlotte

Buses Leaving from Charlotte

Buses Going to Charlotte

Popular Buses Connecting Buffalo

Buses Leaving from Buffalo

Buses Going to Buffalo