Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Hlavní nádraží | Frankfurt Süd | Cheapest | |||||
InterCity + Regional-Express + Deutsche Bahn ICE | Hlavní nádraží | Frankfurt Hbf | Fastest | |||||
Flixbus + Flixtrain | Prague (Central Bus Station Florenc) | Südbahnhof | No tags | |||||
EuroCity Train + Deutsche Bahn ICE + S-Bahn | Hlavní nádraží | Frankfurt am Main Frankfurt West | No tags | |||||
EuroCity Train + Deutsche Bahn ICE | Hlavní nádraží | Frankfurt Hbf | No tags |
Accepted payments
Compare 3 ways to travel from Prague to Frankfurt am Main
| Average price | Average duration | CO₂ emissions | |||
|---|---|---|---|---|---|
| Average priceUS$27 - US$152 | Average duration8h 40m | 10kg CO₂e5 out of 5 stars | Most eco-friendly | ||
| Average priceUS$32 - US$264 | Average duration8h 24m | 10kg CO₂e5 out of 5 stars | |||
Carpool | Average priceUS$22 - US$37 | Average duration5h 20m | 17kg CO₂e4 out of 5 stars | CheapestFastest |
Busbud recommends carpooling from Prague to Frankfurt am MainAmong the sustainable travel choices, the carpool stands out as a good way to reach Frankfurt am Main. The journey takes about 5 hours 20 minutes and with fares starting at just US$22, it presents an excellent value for a comfortable ride.
Train Prague to Frankfurt am Main: Trip Overview
Please note, this information is subject to change.
Train Companies
Prague to Frankfurt am Main Train
Busbud shows you the best train ticket fares and train schedules so you can plan and book a trip by train easily from Prague to Frankfurt am Main.
We make it our job to connect you with the most dependable companies that offer train services from Prague to Frankfurt am Main.
Whether it is train tickets or first class train tickets going to Frankfurt am Main from Prague, we help you find what you're looking for based on how much of a budget you have.
Where are the popular train stations and stops in Prague and Frankfurt am Main?
Frequently asked questions on the trip Prague - Frankfurt am Main
How much does a cheap train ticket from Prague to Frankfurt am Main cost?
The average train ticket price from Prague to Frankfurt am Main is US$88. The best way to find cheap train tickets from Prague to Frankfurt am Main is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Prague to Frankfurt am Main?
A train trip between Prague and Frankfurt am Main is around 8h 24m, although the fastest train will take about 7h 1m. This is the time it takes to travel the 254 miles that separates the two cities.
How many daily train are there between Prague and Frankfurt am Main?
The number of trains from Prague to Frankfurt am Main can differ depending on the day of the week. On average, there are 46. Some trains are direct while others include transferring trains. Simplify your train trip from Prague to Frankfurt am Main by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Prague to Frankfurt am Main?
When taking the train from Prague to Frankfurt am Main, you can travel comfortably and safely with Deutsche Bahn EuroCity, Deutsche Bahn.
What are the departure and arrival stations for a train from Prague to Frankfurt am Main?
Trains travelling between Prague and Frankfurt am Main leave from Hlavní nádraží or Florenc and arrive at Südbahnhof, Frankfurt Airport.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Frankfurt am Main was searched and found on 26 Aug 2025 with a price of US$36To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Frankfurt am Main as early as possible.
You can expect to pay from US$36 to US$212 for a train ticket from Prague to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at US$36, which is on 2025-08-26.
About Train Travel
Train Travel Tips
Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Prague and Frankfurt am Main is also a great way to travel to arrive in the city centre and save more time for your stay in Frankfurt am Main.
Whether you take a regional or high-speed train to Frankfurt am Main, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Prague and Frankfurt am Main, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Create your own real-life musical score by curating a personalised train travel playlist – the perfect accompaniment for your journey from Prague to Frankfurt am Main.
Did you know?
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
Top Travelled Train Routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Trains Connecting Frankfurt am Main
Trains Going to Frankfurt am Main
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