Trains tickets from Boston, MA, US to Greenville, SC

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Today1 Sept
from US$574
Tomorrow2 Sept
from US$352
Wed3 Sept
from US$275
Thu4 Sept
Fri5 Sept
Sat6 Sept
from US$352
Sun7 Sept
from US$445
Mon8 Sept

Trains leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 2 September at
    Departure city: Boston
    Departure location: South Station (Train Terminal)
    Arrival time: 3 September at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 2 September at
    Departure city: Boston
    Departure location: Boston Route 128, MA
    Arrival time: 3 September at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: Amtrak Acela + Amtrak
    Amtrak Acela + Amtrak
    Vehicle: TrainDuration:
  • Departure time: 2 September at
    Departure city: Boston
    Departure location: South Station (Train Terminal)
    Arrival time: 3 September at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: 2 September at
    Departure city: Boston
    Departure location: South Station (Train Terminal)
    Arrival time: 3 September at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: Amtrak Acela + Amtrak
    Amtrak Acela + Amtrak
    Vehicle: TrainDuration:
  • Departure time: 2 September at
    Departure city: Boston
    Departure location: South Station (Train Terminal)
    Arrival time: 3 September at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to travel from Boston to Greenville

Bus
Average priceUS$91 - US$259Average duration23h 5m
32kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$216 - US$838Average duration20h 56m
117kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Boston to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 23 hours 5 minutes and with fares starting at just US$91, it presents an excellent value for a comfortable ride.

9bus per day
23h 5mAverage duration
US$91Cheapest ticket
32kgCO₂ emissions

Train Boston, MA, US to Greenville, SC: Trip Overview

Please note, this information is subject to change.

Average ticket priceUS$345
Average train trip duration20h 56m
Number of daily trains3
Earliest train departure08:12
Distance800 miles
Latest train departure09:25

Boston to Greenville Train

Busbud helps you find a train from Boston to Greenville. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.

Train services from Boston to Greenville will be provided by the most trusted companies.

Whether it is train tickets or first class train tickets going to Greenville from Boston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Boston, MA, US - Greenville, SC

  1. How much does a cheap train ticket from Boston to Greenville cost?

    The average train ticket price from Boston to Greenville is US$345. The best way to find cheap train tickets from Boston to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the train trip from Boston to Greenville?

    A train trip between Boston and Greenville is around 20h 56m, although the fastest train will take about 19h 59m. This is the time it takes to travel the 801 miles that separates the two cities.

  3. How many daily train are there between Boston and Greenville?

    The number of trains from Boston to Greenville can differ depending on the day of the week. On average, there are 3. Some trains are direct while others include transferring trains. Simplify your train trip from Boston to Greenville by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. Which train companies travel from Boston to Greenville?

    When taking the train from Boston to Greenville, you can travel comfortably and safely with Amtrak, Amtrak Acela.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/08
US$338
31/08
US$375
Today
US$553
02/09
US$338
03/09
US$264
04/09
No data
05/09
US$266
06/09
US$338
busbud logoThe cheapest trip from Boston, MA, US to Greenville, SC was searched and found on 3 Sept 2025 with a price of US$264

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Greenville, SC as early as possible.

You can expect to pay from US$264 to US$948 for a train ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$264, which is on 2025-09-03.

About Train Travel

Train Travel Tips

There are many train stations in the world, explore station pages on Busbud to get all information you need.

No matter if you plan to take a regional or high-speed train to Greenville, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.

By choosing the train between Boston and Greenville, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Tune out to the fine sounds of your best music playlist on your train trip from Boston to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.

You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one travelling between the city and the suburbs.

Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.

Will you be returning to Boston, MA, US by train?

Train from Greenville, SC to Boston, MA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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