Find coaches from San Diego, CA, US to Buffalo, NY

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Previously seen journeys

One passenger / one way

  • Departure time: 18 August at
    Departure city: San Diego
    Departure location: San Diego Greyhound Bus Stop
    Arrival time: 22 August at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 18 August at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: 22 August at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 18 August at
    Departure city: San Diego
    Departure location: San Diego Greyhound Bus Stop
    Arrival time: 21 August at
    Destination city: Buffalo
    Destination location: Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States)
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 18 August at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: 21 August at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 18 August at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: 21 August at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

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Compare 2 ways to travel from San Diego to Buffalo

Bus
Average priceUS$234 - US$323Average duration3d 6h
88kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$281 - US$417Average duration2d 15h
321kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from San Diego to Buffalo

Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 3 days, 6 hours and with fares starting at just US$234, it presents an excellent value for a comfortable ride.

18bus per day
3d 6hAverage duration
US$234Cheapest ticket
88kgCO₂ emissions

Bus San Diego, CA, US to Buffalo, NY: Trip Overview

Average ticket priceUS$255
Average bus trip duration3d 6h
Number of daily buses18
Earliest bus departure09:00
Distance2187 miles
Latest bus departure19:35

San Diego to Buffalo Bus

Busbud helps you find a bus from San Diego to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from San Diego to Buffalo will be provided by the most trusted bus companies.

Discover how much the bus trip from San Diego to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Diego, CA, US - Buffalo, NY

  1. How far is Buffalo from San Diego by coach?

    The distance between San Diego and Buffalo by coach is approximately 2181 miles (3518 km).

  2. Is there a way to reach Buffalo from San Diego without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
16/08
No data
17/08
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Today
US$244
19/08
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20/08
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21/08
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22/08
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busbud logoThe cheapest trip from San Diego, CA, US to Buffalo, NY was searched and found on 18 Aug 2025 with a price of US$244

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Buffalo, NY as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Buffalo!

Much more than a mere vehicle taking you from San Diego to Buffalo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Diego to Buffalo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Buffalo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from San Diego, CA, US to Buffalo, NY?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego, CA, US by bus?

Bus from Buffalo, NY to San Diego, CA, US

You can also go to Buffalo, NY by train

Train from San Diego, CA, US to Buffalo, NY

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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