Find coaches from Orlando to Durham, NC, US

Find affordable coach tickets from Orlando to Durham, NC, US with flexible options. Book your journey now

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Today20 Aug
Tomorrow21 Aug
from US$110
Fri22 Aug
from US$108
Sat23 Aug
Sun24 Aug
from US$108
Mon25 Aug
from US$88
Tue26 Aug
from US$103
Wed27 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 21 August at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 22 August at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 21 August at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 22 August at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 21 August at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 21 August at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 21 August at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 22 August at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 21 August at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: 22 August at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Orlando to Durham

Bus
Average priceUS$88 - US$209Average duration17h 15m
22kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average priceUS$67 - US$199Average duration15h 40m
79kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from Orlando to Durham

Among the sustainable travel choices, the train stands out as a good way to reach Durham. The journey takes about 15 hours 40 minutes and with fares starting at just US$67, it presents an excellent value for a comfortable ride.

1train per day
15h 40mAverage duration
US$67Cheapest ticket
79kgCO₂ emissions

Bus Orlando to Durham, NC, US: Trip Overview

Average ticket priceUS$115
Average bus trip duration17h 15m
Number of daily buses7
Earliest bus departure04:45
Distance534 miles
Latest bus departure22:55

Orlando to Durham Bus

Busbud helps you find a bus from Orlando to Durham. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Orlando to Durham.

Discover how much the bus trip from Orlando to Durham will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Orlando - Durham, NC, US

  1. What's the distance between Orlando and Durham by coach?

    The journey from Orlando to Durham by coach covers an approximate distance of 535 miles (863 km).

  2. How can I travel from Orlando to Durham avoiding air travel?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/08
No data
19/08
US$103
Today
US$96
21/08
US$102
22/08
US$100
23/08
No data
24/08
US$100
25/08
US$80
busbud logoThe cheapest trip from Orlando to Durham, NC, US was searched and found on 25 Aug 2025 with a price of US$80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Durham, NC, US as early as possible.

You can expect to pay from US$80 to US$122 for a bus ticket from Orlando to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$80, which is on 2025-08-25.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Orlando and Durham!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Orlando to Durham.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Orlando to Durham will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Orlando to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Orlando to Durham, NC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Orlando by bus?

Bus from Durham, NC, US to Orlando

You can also go to Durham, NC, US by train

Train from Orlando to Durham, NC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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