Find coaches from Des Moines to Syracuse, US

Busbud helps you find a bus from Des Moines to Syracuse. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Syracuse from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Des Moines to Syracuse, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Syracuse!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Syracuse, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Syracuse that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Des Moines to Syracuse.