Find coaches from Des Moines to Milwaukee

Find affordable coach tickets from Des Moines to Milwaukee with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today2 Sept
Tomorrow3 Sept
from US$73
Thu4 Sept
from US$56
Fri5 Sept
from US$62
Sat6 Sept
from US$62
Sun7 Sept
Mon8 Sept
from US$67
Tue9 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 3 September at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: 3 September at
    Destination city: Milwaukee
    Destination location: Milwaukee Bus Station, St. Paul & N6th road.
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 3 September at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: 3 September at
    Destination city: Milwaukee
    Destination location: Milwaukee Mitchell MKE Airport
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: 3 September at
    Destination city: Milwaukee
    Destination location: Milwaukee Mitchell MKE Airport
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Des Moines
    Departure location: Des Moines
    Arrival time: 4 September at
    Destination city: Milwaukee
    Destination location: St. Paul & N5th
    Operated by: Jefferson LinesJefferson Lines
    Vehicle: BusDuration:
  • Departure time: 3 September at
    Departure city: Des Moines
    Departure location: Des Moines
    Arrival time: 4 September at
    Destination city: Milwaukee
    Destination location: St. Paul & N5th
    Operated by: Jefferson Lines + Land to Air Express
    Jefferson Lines + Land to Air Express
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Des Moines to Milwaukee: Trip Overview

Average ticket priceUS$69
Average bus trip duration11h 35m
Number of daily buses3
Earliest bus departure04:20
Distance306 miles
Latest bus departure23:30

Des Moines to Milwaukee Bus

Busbud helps you find a bus from Des Moines to Milwaukee. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Milwaukee from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Milwaukee from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Des Moines - Milwaukee

  1. What's the distance between Des Moines and Milwaukee by coach?

    The journey from Des Moines to Milwaukee by coach covers an approximate distance of 308 miles (496 km).

  2. How can I travel from Des Moines to Milwaukee avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/08
No data
01/09
No data
Today
No data
03/09
US$168
04/09
No data
05/09
No data
06/09
No data
07/09
No data
busbud logoThe cheapest trip from Des Moines to Milwaukee was searched and found on 3 Sept 2025 with a price of US$168

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Milwaukee as early as possible.

You can expect to pay from US$168 to US$168 for a bus ticket from Des Moines to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at US$168, which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Milwaukee!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Milwaukee, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Milwaukee.

Make a music playlist for your bus ride from Des Moines to Milwaukee, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Des Moines by bus?

Bus from Milwaukee to Des Moines

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines

Popular Buses Connecting Milwaukee

Buses Leaving from Milwaukee

Buses Going to Milwaukee