Bus Tickets from Santa Bárbara, CL to Santiago, CL

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Previously seen trips

One passenger / one way

  • Departure time: September 7 at
    Departure city: Santa Bárbara
    Departure location: Santa Bárbara
    Arrival time: September 8 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: Eme BusEme Bus
    Vehicle: BusDuration:
  • Departure time: September 27 at
    Departure city: Santa Bárbara
    Departure location: Santa Bárbara
    Arrival time: September 27 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: Eme BusEme Bus
    Vehicle: BusDuration:
  • Departure time: September 27 at
    Departure city: Santa Bárbara
    Departure location: Santa Bárbara
    Arrival time: September 27 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: Eme BusEme Bus
    Vehicle: BusDuration:
  • Departure time: October 7 at
    Departure city: Santa Bárbara
    Departure location: Santa Bárbara
    Arrival time: October 8 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: Eme BusEme Bus
    Vehicle: BusDuration:
  • Departure time: November 3 at
    Departure city: Santa Bárbara
    Departure location: Santa Bárbara
    Arrival time: November 3 at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: Eme BusEme Bus
    Vehicle: BusDuration:

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Bus Santa Bárbara, CL to Santiago, CL: Trip Overview

Average Ticket PriceUS$15
Average Bus Trip Duration5h 53m
Number of daily buses2
Earliest bus departure5:50am
Distance483 km
Latest bus departure9:50pm

Santa Bárbara to Santiago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Bárbara to Santiago.

Bus service from Santa Bárbara to Santiago will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santa Bárbara to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Bárbara, CL - Santiago, CL

  1. How far is Santa Bárbara from Santiago?

    The distance between Santa Bárbara and Santiago is approximately 490 km (304 miles).

  2. What are the departure and arrival locations for buses traveling from Santa Bárbara to Santiago?

    Buses departing from Terminal Buses Aranguiz de Santa Bárbara in Santa Bárbara will take you to Terminal Sur in Santiago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-25
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08-26
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Today
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08-28
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08-29
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08-30
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08-31
US$14
09-01
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busbud logoThe cheapest trip from Santa Bárbara, CL to Santiago, CL was searched and found on Aug 31, 2025 with a price of US$14

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Bárbara, CL to Santiago, CL, as early as possible.

You can expect to pay from US$14 to US$25 for a bus ticket from Santa Bárbara, CL to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at US$14 which is on 2025-08-31.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Bárbara to Santiago but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santa Bárbara to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Bárbara to Santiago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Bárbara to Santiago.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santa Bárbara, CL by bus?

Bus from Santiago, CL to Santa Bárbara, CL

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