Bus Tickets from Santa Ana, US to Calexico

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TodayAug 16
TomorrowAug 17
MonAug 18
from US$45
TueAug 19
from US$41
WedAug 20
ThuAug 21
FriAug 22
SatAug 23

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 18 at
    Departure city: Santa Ana
    Departure location: Santa Ana Bus Station
    Arrival time: August 18 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 18 at
    Departure city: Santa Ana
    Departure location: Anaheim Regional Transportation Intermodal Center
    Arrival time: August 18 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 18 at
    Departure city: Santa Ana
    Departure location: Anaheim Regional Transportation Intermodal Center
    Arrival time: August 18 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 18 at
    Departure city: Santa Ana
    Departure location: Anaheim Regional Transportation Intermodal Center
    Arrival time: August 18 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 18 at
    Departure city: Santa Ana
    Departure location: Santa Ana Bus Station
    Arrival time: August 18 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Santa Ana, US to Calexico: Trip Overview

Average Ticket PriceUS$45
Average Bus Trip Duration9h 5m
Number of daily buses3
Earliest bus departure7:40am
Distance255 km
Latest bus departure10:25am

Santa Ana to Calexico Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Ana to Calexico.

Bus service from Santa Ana to Calexico will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santa Ana to Calexico, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Ana, US - Calexico

  1. How far is Santa Ana from Calexico?

    The distance between Santa Ana and Calexico is approximately 248 km (154 miles).

  2. What are the departure and arrival locations for buses traveling from Santa Ana to Calexico?

    Buses departing from Santa Ana Greyhound Bus Station in Santa Ana will take you to Calexico Bus Station in Calexico.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-14
US$34
08-15
US$41
Today
US$41
08-17
No data
08-18
US$37
08-19
No data
08-20
US$30
08-21
No data
busbud logoThe cheapest trip from Santa Ana, US to Calexico was searched and found on Aug 20, 2025 with a price of US$30

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Calexico, as early as possible.

You can expect to pay from US$30 to US$41 for a bus ticket from Santa Ana, US to Calexico based on the last 2 days. You can expect to find the cheapest price for the trip at US$30 which is on 2025-08-20.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Ana to Calexico but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santa Ana to Calexico, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Ana to Calexico that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Ana to Calexico.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santa Ana, US by bus?

Bus from Santa Ana, US to Calexico

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