Bus Tickets from San Diego, CA, US to San Antonio, US

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TodayAug 20
TomorrowAug 21
FriAug 22
from US$146
SatAug 23
SunAug 24
from US$136
MonAug 25
TueAug 26
WedAug 27

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 22 at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: August 24 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 22 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: August 23 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: August 22 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: August 24 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 22 at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: August 24 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Valley Transit
    FlixBus + Greyhound Lines, Inc. + Valley Transit
    Vehicle: BusDuration:
  • Departure time: August 22 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: August 23 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Greyhound Lines Mexico
    Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:

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Compare 2 ways to go from San Diego to San Antonio

Average PriceUS$110 - US$454Average Duration1d 13h
45kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average PriceUS$159 - US$299Average Duration1d 10h
165kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from San Diego to San Antonio

Among the sustainable travel choices, the train stands out as a good way to reach San Antonio. The journey takes about 1 day, 10 hours 50 minutes, and with fares starting at just US$159, it presents an excellent value for a comfortable ride.

2train per day
1d 10hAverage Duration
US$159Cheapest ticket
165kgCO₂ emissions

Bus San Diego, CA, US to San Antonio, US: Trip Overview

Average Ticket PriceUS$151
Average Bus Trip Duration1d 13h
Number of daily buses9
Earliest bus departure7:15am
Distance1817 km
Latest bus departure7:35pm

San Diego to San Antonio Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Diego to San Antonio.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to San Antonio.

Whether it is cheap bus tickets or more luxurious buses going to San Antonio from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip San Diego, CA, US - San Antonio, US

  1. What is the distance between San Diego and San Antonio?

    The distance between San Diego and San Antonio is around 1815 km (1125 miles).

  2. What are the departure and arrival locations for buses traveling from San Diego to San Antonio?

    Buses traveling this route start their trip at Mission Valley Sheraton, in San Diego, and end it at San Antonio Bus Station, in San Antonio.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-18
US$105
08-19
US$163
Today
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08-21
No data
08-22
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08-23
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08-24
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08-25
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busbud logoThe cheapest trip from San Diego, CA, US to San Antonio, US was searched and found on Aug 18, 2025 with a price of US$105

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to San Antonio, US, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Diego to San Antonio but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Diego to San Antonio.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to San Antonio.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to San Antonio.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from San Diego, CA, US to San Antonio, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego, CA, US by bus?

Bus from San Antonio, US to San Diego, CA, US

You can also go to San Antonio, US by train

Train from San Diego, CA, US to San Antonio, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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