Bus Tickets from New Castle to St. Louis

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TodayAug 22
TomorrowAug 23
SunAug 24
MonAug 25
TueAug 26
from US$118
WedAug 27
ThuAug 28
FriAug 29

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 26 at
    Departure city: New Castle
    Departure location: Route 422 Park & Ride
    Arrival time: August 27 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus New Castle to St. Louis: Trip Overview

Average Ticket PriceUS$118
Average Bus Trip Duration16h 25m
Number of daily buses1
Earliest bus departure3:00pm
Distance887 km

New Castle to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from New Castle to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from New Castle to St. Louis will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from New Castle to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip New Castle - St. Louis

  1. What is the travel distance from New Castle to St. Louis?

    It's about 888 km (551 miles) from New Castle to St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-20
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08-21
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Today
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08-23
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08-24
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08-25
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08-26
US$110
08-27
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busbud logoThe cheapest trip from New Castle to St. Louis was searched and found on Aug 26, 2025 with a price of US$110

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Castle to St. Louis, as early as possible.

You can expect to pay from US$110 to US$110 for a bus ticket from New Castle to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$110 which is on 2025-08-26.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from New Castle to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from New Castle to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from New Castle to St. Louis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from New Castle to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

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