Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Jacksonville Bus Station | Downtown Transit Center | Cheapest | |||||
FlixBus + Greyhound Lines, Inc. | Jacksonville Bus Station | Indianapolis Bus Station | Fastest | |||||
FlixBus + Greyhound Lines, Inc. | Jacksonville Bus Station | Indianapolis Bus Station | No tags | |||||
 | Jacksonville Bus Station | Indianapolis Bus Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Jacksonville Bus Station | Indianapolis Bus Station | No tags |
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Compare 2 ways to go from Jacksonville to Indianapolis
Busbud recommends taking the bus from Jacksonville to IndianapolisAmong the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 1 day, and with fares starting at just US$88, it presents an excellent value for a comfortable ride.
Bus Jacksonville, FL to Indianapolis: Trip Overview
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Jacksonville to Indianapolis Bus
Busbud helps you find a bus from Jacksonville to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Jacksonville to Indianapolis from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from Jacksonville to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Jacksonville and Indianapolis?
Frequently asked questions on the trip Jacksonville, FL - Indianapolis
What is the travel distance from Jacksonville to Indianapolis?
The distance between Jacksonville and Indianapolis is approximately 1128 km (699 miles).
What are the departure and arrival locations for buses traveling from Jacksonville to Indianapolis?
Buses departing from Jacksonville Amtrak Station in Jacksonville will take you to Greyhound Amtrak Station in Indianapolis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Indianapolis was searched and found on Sep 4, 2025 with a price of US$109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Indianapolis, as early as possible.
You can expect to pay from US$109 to US$221 for a bus ticket from Jacksonville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$109 which is on 2025-09-04.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Jacksonville and Indianapolis!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Indianapolis, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jacksonville to Indianapolis that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Jacksonville to Indianapolis while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from Jacksonville, FL to Indianapolis?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Popular Buses Connecting Jacksonville
Buses Leaving from Jacksonville
- Bus from Jacksonville to Jacksonville
- Bus Jacksonville - Miami
- Jacksonville - Atlanta
- Bus from Jacksonville to Savannah
- Bus Jacksonville - Gainesville
- Jacksonville - Gainesville
- Bus from Jacksonville to Orlando
- Bus Jacksonville - Columbus
- Jacksonville - New York City
- Bus from Jacksonville to Ocala
- Bus Jacksonville - Roanoke
- Jacksonville - Lafayette
- Bus from Jacksonville to Corpus Christi
- Bus Jacksonville - Port Saint Lucie
- Jacksonville - Key West
Buses Going to Jacksonville
- Bus from Jacksonville to Jacksonville
- Bus Orlando - Jacksonville
- Tampa - Jacksonville
- Bus from Miami to Jacksonville
- Bus San Marcos - Jacksonville
- Boston - Jacksonville
- Bus from Gainesville to Jacksonville
- Bus Atlanta - Jacksonville
- Port Saint Lucie - Jacksonville
- Bus from Buffalo to Jacksonville
- Bus Columbus - Jacksonville
- Meridian - Jacksonville
- Bus from New York City to Jacksonville
- Bus Daytona Beach - Jacksonville
- Houston - Jacksonville
Popular Buses Connecting Indianapolis
Buses Leaving from Indianapolis
- Bus from Indianapolis to Muncie
- Bus Indianapolis - Chicago
- Indianapolis - Bloomington
- Bus from Indianapolis to Bloomington
- Bus Indianapolis - Nashville
- Indianapolis - Temple
- Bus from Indianapolis to St. Louis
- Bus Indianapolis - Columbus
- Indianapolis - Corpus Christi
- Bus from Indianapolis to Madison
- Bus Indianapolis - Newark
- Indianapolis - South Bend
- Bus from Indianapolis to Ashland
- Bus Indianapolis - Detroit
- Indianapolis - New York City
Buses Going to Indianapolis
- Bus from Bloomington to Indianapolis
- Bus Bloomington - Indianapolis
- South Bend - Indianapolis
- Bus from Greenfield to Indianapolis
- Bus Merrillville - Indianapolis
- Terre Haute - Indianapolis
- Bus from Chicago to Indianapolis
- Bus St. Louis - Indianapolis
- Detroit - Indianapolis
- Bus from New York City to Indianapolis
- Bus Toledo - Indianapolis
- London - Indianapolis
- Bus from Buffalo to Indianapolis
- Bus Columbus - Indianapolis
- Philadelphia - Indianapolis
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Albany - New York City
- Bus from Baton Rouge to New Orleans
- Bus Los Angeles - San Francisco
- Miami - Orlando
- Bus from Los Angeles to San Diego
- Bus Las Vegas - Los Angeles
- Atlanta - Savannah